4-[2-(3-methylquinoxalin-2-yloxy)ethoxy]benzoic acid methyl ester | 814920-69-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 4-[2-(3-methylquinoxalin-2-yloxy)ethoxy]benzoic acid methyl ester
• 英文别名: Methyl 4-[2-(3-methylquinoxalin-2-yl)oxyethoxy]benzoate
• CAS: 814920-69-9
• 化学式: C₁₉H₁₈N₂O₄
• 分子量: 338.363
• InChiKey: RRIKCTPGZLYVPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  70.5
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• NEW BENZAMIDES AS PPATY MODULATORS
  申请人：LABORATORIOS S.A.L.V.A.T., S.A.

  公开号：EP1644321B1

  公开（公告）日：2011-02-09
• [EN] NEW BENZAMIDES AS PPRTϒ MODULATORS<br/>[FR] NOUVEAUX BENZAMIDES EN TANT QUE MODULATEURS DE PPAR DOLLAR G(G)
  申请人：S A L V A T LAB SA

  公开号：WO2004110983A2

  公开（公告）日：2004-12-23

  Compounds of general structure (I), wherein the central benzene ring may be substituted in the meta- or para-­position; -A is an optionally substituted hydroxyl, alkoxyl, hydroxylamine, alkoxylamine or amine radical; -W is an N- ­and C-linked biradical selected from several possibilities; and -Z is a carbon radical selected from several possibilities. These compounds are PPARϒ and PPARϒ/ PPARδ modulators and, therefore, are useful for the prophylactic and/or curative treatment of a condition or a disease mediated by these recetpcors.