bis-(2-acetoxy-[1]naphthyl)-sulfide | 60930-64-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: bis-(2-acetoxy-[1]naphthyl)-sulfide
• 英文别名: Bis-(2-acetoxy-[1]naphthyl)-sulfid；2.2'-Diacetoxy-1.1'-dinaphthylsulfid；[1-(2-Acetyloxynaphthalen-1-yl)sulfanylnaphthalen-2-yl] acetate
• CAS: 60930-64-5
• 化学式: C₂₄H₁₈O₄S
• 分子量: 402.471
• InChiKey: ZQLWFARPOIUACH-UHFFFAOYSA-N

物化性质

• 熔点：
  198 °C
• 沸点：
  547.2±35.0 °C(Predicted)
• 密度：
  1.33±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  29
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  77.9
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  bis-(2-acetoxy-[1]naphthyl)-sulfide 在 溴 、 溶剂黄146 作用下， 生成 1,6-二溴-2-萘酚
  参考文献：
  名称：

  Rege; Airan; Shah, Journal of the Indian Chemical Society, 1948, vol. 25, p. 43,44

  摘要：

  DOI：
• 作为产物：
  描述：

  1,1'-trisulfanediylbis(naphthalen-2-ol) 生成 bis-(2-acetoxy-[1]naphthyl)-sulfide
  参考文献：
  名称：

  Airan; Shah, Journal of the Indian Chemical Society, 1945, vol. 22, p. 359,361

  摘要：

  DOI：

文献信息

• Human Papillomavirus and Risk of Laryngeal Cancer
  作者：Elaine M. Smith、Kurt F. Summersgill、Timothy McCulloch、Jeffrey Allen、Lubomir P. Turek、Henry T. Hoffman、Thomas H. Haugen

  DOI：10.1177/000348940010901114

  日期：2000.11

  We determined the relationship between human papillomavirus (HPV) infection and the HPV types detected in 44 patients with squamous cell carcinoma, 10 laryngeal leukoplakia patients, and 12 patients evaluated for benign laryngeal conditions (controls). The sources of HPV DNA were from brushings from the upper respiratory tract and lesion (benign or malignant), oral rinses, and biopsies of patient lesions. Polymerase chain reaction (PCR) and DNA sequencing were used to identify and type HPV. We detected HPV in 25.0% (11/44) of patients with laryngeal cancer, in 30.0% (3/10) of patients with laryngeal leukoplakia, and in 16.7% (2/12) of noncancer controls. Patients with cancer were not more likely to be identified with oncogenic HPV types (18.2%) than either the leukoplakia group (20%) or the control group (16.7%). An increased risk of disease was associated with current tobacco use and former alcohol drinking in cancer patients versus controls and in leukoplakia patients versus controls (all p < .05). After we controlled for tobacco and alcohol effects on the risk of disease, exposure to oncogenic HPV types was associated with an increased risk of laryngeal cancer (odds ratio = 3.0) and of laryngeal leukoplakia (odds ratio = 6.0) compared to controls, although the results were not statistically significant. This study suggests that although HPV infection and HPV oncogenic types are not found at a higher frequency in laryngeal cancer or laryngeal leukoplakia as compared to controls, infection is associated with an increased risk of disease after controlling for the effects of alcohol and tobacco use.

  我们确定了人乳头瘤病毒（HPV）感染与44名鳞状细胞癌患者、10名喉白斑患者和12名良性喉部疾病患者（对照组）检测到的HPV类型之间的关系。HPV DNA的来源包括来自上呼吸道和病变（良性或恶性）的刷拭、口腔漱洗和患者病变的活检。使用聚合酶链反应（PCR）和DNA测序来鉴定和分类HPV。我们在44名喉癌患者中检测到25.0%（11/44）的HPV，在10名喉白斑患者中检测到30.0%（3/10）的HPV，在非癌症对照组中检测到16.7%（2/12）的HPV。癌症患者更有可能被识别为致癌性HPV类型（18.2%）而不是白斑组（20%）或对照组（16.7%）。与对照组相比，癌症患者与白斑患者与疾病风险增加相关联，与目前吸烟和过去饮酒有关（所有p < .05）。在控制烟草和酒精对疾病风险的影响后，暴露于致癌性HPV类型与增加患喉癌（比值比=3.0）和患喉白斑（比值比=6.0）的风险相关联，尽管结果在统计学上不显著。该研究表明，尽管与对照组相比，在喉癌或喉白斑中HPV感染和HPV致癌类型的频率并不更高，但在控制酒精和烟草使用的影响后，感染与疾病风险增加相关联。
• Effect of Moisture Content on the Thermomechanical Behavior of Concentrated Waxy Cornstarch–Water Preparations— A Comparison with Wheat Starch
  作者：A. Rolee、E. Chiotelli、M. Le Meste

  DOI：10.1111/j.1365-2621.2002.tb09451.x

  日期：2002.4

  ABSTRACT: The rheological behavior of waxy cornstarch preparations at intermediate moisture contents (30 to 60% w/w) was studied by dynamic mechanical thermal analysis (DMTA). Differential scanning calorimetry (DSC) and electron spin resonance (ESR) experiments were also performed in parallel. The results were compared to those obtained previously for wheat starch. DMTA results evidenced a critical moisture content (between 50 and 55%) for waxy cornstarch that delimited a radical change in the rheological behavior both at room temperature and during heating. This critical water content was around 45% for wheat starch.
• Hinsberg, Journal fur praktische Chemie (Leipzig 1954), 1916, vol. <2> 93, p. 281
  作者：Hinsberg

  DOI：——

  日期：——
• Data- and metrics-driven approach to human resource practices: Using customers, employees, and financial metrics
  作者：Thomas E. Murphy、Sourushe Zandvakili

  DOI：10.1002/(sici)1099-050x(200021)39:1<93::aid-hrm8>3.0.co;2-n

  日期：——

  Should scientific measures be used to evaluate the effectiveness of HRM practices? Can HRM demonstrate that its proposals cause a predicted outcome? If the allocation of capital within an organization is based upon projected financial returns, should HRM be required to demonstrate the expected returns of its proposals? Would the use od scientific and financial measures give HRM practices greater internal support and continuity? The authors demonstrate how metrics used to evaluate two new HRM projects at one of the world's largest retailers. (C) 2000 John Wiley & Sons, Ins.
• Onufrowicz, Chemische Berichte, 1888, vol. 21, p. 3562
  作者：Onufrowicz

  DOI：——

  日期：——