2-(2-(3-((1,3-二氢-1,1-二甲基-3-(3-磺基丙基)-2H-苯并(e)吲哚-2-亚基)乙亚基)-2-(4-(乙氧羰基)-1-哌嗪基)-1-环戊烯-1-基)乙烯基)-1,1-二甲基-3-(3-磺基丙基)-1H-苯并(e)吲哚鎓内盐N,N-二乙基乙胺(1:1) | 54849-69-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 2-(2-(3-((1,3-二氢-1,1-二甲基-3-(3-磺基丙基)-2H-苯并(e)吲哚-2-亚基)乙亚基)-2-(4-(乙氧羰基)-1-哌嗪基)-1-环戊烯-1-基)乙烯基)-1,1-二甲基-3-(3-磺基丙基)-1H-苯并(e)吲哚鎓内盐N,N-二乙基乙胺(1:1)
• 英文名称: triethylamine 3-(2-((E)-2-((Z)-3-((Z)-2-(1,1-dimethyl-3-(3-sulfonatopropyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)ethylidene)-2-(4-(ethoxycarbonyl)piperazin-1-yl)cyclopent-1-en-1-yl)vinyl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)propane-1-sulfonate
• 英文别名: N,N-diethylethanamine;3-[(2E)-2-[(2E)-2-[(3Z)-3-[(2Z)-2-[1,1-dimethyl-3-(3-sulfopropyl)benzo[e]indol-2-ylidene]ethylidene]-2-(4-ethoxycarbonylpiperazin-1-ium-1-ylidene)cyclopentylidene]ethylidene]-1,1-dimethylbenzo[e]indol-3-yl]propane-1-sulfonate
• CAS: 54849-69-3
• 化学式: C₆H₁₅N*C₅₀H₅₈N₄O₈S₂
• 分子量: 1008.36
• InChiKey: CLQSKAVTPLZPDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.79
• 重原子数：
  71
• 可旋转键数：
  14
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  171
• 氢给体数：
  1
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  2-(2-(3-((1,3-二氢-1,1-二甲基-3-(3-磺基丙基)-2H-苯并(e)吲哚-2-亚基)乙亚基)-2-(4-(乙氧羰基)-1-哌嗪基)-1-环戊烯-1-基)乙烯基)-1,1-二甲基-3-(3-磺基丙基)-1H-苯并(e)吲哚鎓内盐N,N-二乙基乙胺(1:1) 、 1,3-丙二醇 在 三乙胺 作用下， 反应 20.0h， 以79%的产率得到
  参考文献：
  名称：

  用于 DNA 测序的改性近红外激光染料的光谱表征和评价

  摘要：

  IR-144 的几种衍生物，一种市售的近红外（近红外）激光染料，已与不同的部分合成，这些部分会产生最大吸光度的红移，而不会影响它们的荧光发射光谱。有了这种能力，可以调整染料的最大吸光度，使其与各种半导体激光二极管的最大输出波长一致。此功能允许与具有不同激发源但具有通用近红外检测器的多染料荧光系统兼容。IR-144 衍生物的吸光度最大值接近市售半导体激光二极管的输出波长的效用通过将含有氨基接头的寡核苷酸引物与染料衍生物偶联，并使用专门设计用于近光检测的仪器对 DNA 进行测序来说明。 -红外检测。在进行测序反应之前，近红外激光染料-DNA 偶联物通过反相高效液相色谱纯化。我们报告了 IR-144 衍生物的合成和光谱表征。此外，还讨论了近红外激光染料与氨基修饰的寡核苷酸之间的偶联反应以及随后的纯化。提供了验证标记 DNA 链的亚飞摩尔检测的数据。在进行测序反应之前，近红外激光染料-DNA 偶联物通过反相高效液相色谱纯化。我们报告了

  DOI：

  10.1366/0003702953965858

文献信息

• VERFAHREN ZUM MARKIEREN VON MATERIALIEN
  申请人：BASF Aktiengesellschaft

  公开号：EP1756169A2

  公开（公告）日：2007-02-28
• MIKROKAPSELN, IHRE HERSTELLUNG UND VERWENDUNG
  申请人：BASF SE

  公开号：EP2262863B1

  公开（公告）日：2013-09-04
• ITERATIVE FLUORESCENCE IMAGING
  申请人：Universität Zürich

  公开号：EP3785032A1

  公开（公告）日：2021-03-03
• Method for Marking Materials
  申请人：Champ Simon

  公开号：US20080042106A1

  公开（公告）日：2008-02-21

  The invention relates to a method for the marking of materials with coded microparticies, wherein coded microparticles which are obtainable by (i) polymerization of at least one water-soluble monoethylenically unsaturated monomer in the presence of at least one ethylenically unsaturated monomer having at least two double bonds in the molecule by inverse water-in-oil suspension polymerization, doped nanoparticles being used as the suspending medium, (ii) emulsion polymerization of water-insoluble monoethylenically unsaturated monomers with from 0 to 10% by weight, based on the monomer mixture, of at least one ethylenically unsaturated monomer having at least two double bonds in the molecule, doped nanopartices being used as an emulsifier for stabilizing the disperse phase, (iii) polymerization of at least one ethylenically unsaturated monomer together with a copolymerizable dye which has an ethylenically unsaturated double bond, and, if appropriate, agglomeration of these partices or (iv) agglomeration of at least two different groups of microparticles which differ in their absorption, emission and/or scattering of electromagnetic radiation to give aggregates having a mean particle diameter of from 300 μm to 500 μm are used, the use of the coded microparticles for the marking of materials and the materials marked with the microparticles.
• MICROCAPSULES, THEIR PREPARATION AND USE
  申请人：Jung Marc Rudolf

  公开号：US20100327216A1

  公开（公告）日：2010-12-30

  Microcapsules, comprising (A) in the range from 50 to 95 parts by weight, lipophilic core material which has a solid/liquid phase transition in the temperature range from −20 to 120° C., (B) in the range from 4 to 50 parts by weight, capsule wall, and (C) in the range from 0.01 to 10 parts by weight, at least one colored or color-imparting substance selected from oil-soluble dyes and oil-soluble brighteners, where data in parts by weight are based on the total weight of the microcapsules in question.