2-benzoyloxy-benzo[de]isoquinoline-1,3-dione | 38863-02-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: 2-benzoyloxy-benzo[de]isoquinoline-1,3-dione
• 英文别名: 2-benzoyloxy-benz[de]isoquinoline-1,3-dione；2-Benzoyloxy-benz[de]isochinolin-1,3-dion；1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl benzoate；(1,3-dioxobenzo[de]isoquinolin-2-yl) benzoate
• CAS: 38863-02-4
• 化学式: C₁₉H₁₁NO₄
• mdl: MFCD04444225
• 分子量: 317.301
• InChiKey: QONFYXBWZXAGKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  63.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N-羟基-1,8-萘二甲酰亚胺 、 苯甲酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 2-benzoyloxy-benzo[de]isoquinoline-1,3-dione
  参考文献：
  名称：

  N-Aroyloxynaphthalimides as novel highly efficient DNA photocleavers: substituent effects

  摘要：

  A novel DNA photocleaver family of N-benzovloxythioxonaphthalimides. which show improved DNA intercalation and photocleaving activity compared with their oxo- counterparts, were synthesized and evaluated. The substituents on the benzene ring of the benzoyloxy moiety have an important and unusual influence on the DNA photocleaving activity. N-(p-Methoxylbenzovloxy)thioxonaphthalimide is able to photocleave DNA at low concentration (5 muM) with 'time-resolved' and pH independent properties. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01214-x

文献信息

• Use of organic oxyimides as flame retardant for plastic materials and also flame-retardant plastic material composition and moulded parts produced therefrom
  申请人：FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.

  公开号：US10913743B2

  公开（公告）日：2021-02-09

  The present invention relates to the use of organic oxy imides as flame retardants for plastics. According to the present invention, a flame-retardant plastics composition is likewise specified, including an oxy imide as flame retardant. Additionally specified are mouldings produced from an inventive flame-retardant polymer composition.

  本发明涉及有机含氧亚胺作为塑料阻燃剂的用途。根据本发明，同样规定了一种阻燃塑料组合物，包括一种作为阻燃剂的含氧亚胺。此外，还具体说明了用本发明的阻燃聚合物组合物生产的模具。
• Yamazaki, Yuki Gosei Kagaku Kyokaishi, 1955, vol. 13, p. 232
  作者：Yamazaki

  DOI：——

  日期：——
• N-Aroyloxynaphthalimides as novel highly efficient DNA photocleavers: substituent effects
  作者：Xuhong Qian、Wei Yao、Gang Chen、Xiayu Huang、Ping Mao

  DOI：10.1016/s0040-4039(01)01214-x

  日期：2001.8

  A novel DNA photocleaver family of N-benzovloxythioxonaphthalimides. which show improved DNA intercalation and photocleaving activity compared with their oxo- counterparts, were synthesized and evaluated. The substituents on the benzene ring of the benzoyloxy moiety have an important and unusual influence on the DNA photocleaving activity. N-(p-Methoxylbenzovloxy)thioxonaphthalimide is able to photocleave DNA at low concentration (5 muM) with 'time-resolved' and pH independent properties. (C) 2001 Elsevier Science Ltd. All rights reserved.