| 1402818-90-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• CAS: 1402818-90-9
• 化学式: C₃₇H₃₉N₇O₃
• 分子量: 629.762
• InChiKey: QTVRIFCSDPNENG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.22
• 重原子数：
  47.0
• 可旋转键数：
  10.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  115.86
• 氢给体数：
  2.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  、 copper dichloride 在 4-羟乙基哌嗪乙磺酸 作用下， 以 乙醇 、 水 为溶剂， 生成
  参考文献：
  名称：

  Characterization of a highly Cu2+-selective fluorescent probe derived from rhodamine B

  摘要：

  A rhodamine B derivative was synthesized and characterized as a highly selective and sensitive probe for Cu2+ in ethanol-water solution (2:3, v:v, pH7.4, 50 mM HEPES). A prominent fluorescence enhancement at 575 nm was observed in the presence of Cu2+, accompanied by the change in the absorption spectrum. Under the optimal conditions, a good linear range of 0.5-1.5 mu M with a detection limit of 1.6 x 10(-7) M were obtained. Furthermore, confocal laser scanning microscopy experiments have proven that this probe is cell-permeable and can respond to changes in intracellular Cu2+ in living cells. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.07.016
• 作为产物：
  描述：

  在 乙二胺四乙酸 作用下， 生成
  参考文献：
  名称：

  Characterization of a highly Cu2+-selective fluorescent probe derived from rhodamine B

  摘要：

  A rhodamine B derivative was synthesized and characterized as a highly selective and sensitive probe for Cu2+ in ethanol-water solution (2:3, v:v, pH7.4, 50 mM HEPES). A prominent fluorescence enhancement at 575 nm was observed in the presence of Cu2+, accompanied by the change in the absorption spectrum. Under the optimal conditions, a good linear range of 0.5-1.5 mu M with a detection limit of 1.6 x 10(-7) M were obtained. Furthermore, confocal laser scanning microscopy experiments have proven that this probe is cell-permeable and can respond to changes in intracellular Cu2+ in living cells. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2012.07.016