Sulfuric acid mono-[4-(3-tert-butylamino-2-hydroxy-propoxy)-2,3-dimethyl-phenyl] ester | 56323-38-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: Sulfuric acid mono-[4-(3-tert-butylamino-2-hydroxy-propoxy)-2,3-dimethyl-phenyl] ester
• CAS: 56323-38-7
• 化学式: C₁₅H₂₅NO₆S
• 分子量: 347.433
• InChiKey: KUNHJQHOJCFEHR-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  Sulfuric acid mono-[4-(3-tert-butylamino-2-hydroxy-propoxy)-2,3-dimethyl-phenyl] ester 在 盐酸 作用下， 以 甲醇 为溶剂， 生成 1-tert-Butylamino-3-(2.3-dimethyl-4-hydroxyphenoxy)-2-propanol
  参考文献：
  名称：

  Isolation and characterization of metabolites derived from 1-tert-butylamino-3-(2,3-dimethylphenoxy)-2-propanol D-32), a new .BETA.-blocker.

  摘要：

  The metabolic fate of D-32, which is a new adrenergic β-blocking agent, has been investigated with rabbit, rat and monkey. Eleven unconjugated metabolites and four conjugated metabolites were separated from urine after oral administration of D-32. The structure of these metabolites were deduced from physico-chemical data and definitely characterized by direct comparison with the authentic samples (see Chart 1). The biochemical significance of the transformation observed and the pharmacological activity of metabolites have been discussed.

  DOI：

  10.1248/cpb.23.1045