3β.5-dihydroxy-5β-cholestanone-(6)-dimethylacetal | 20104-88-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3β.5-dihydroxy-5β-cholestanone-(6)-dimethylacetal
• 英文别名: 3β.5-Dihydroxy-5β-cholestanon-(6)-dimethylacetal
• CAS: 20104-88-5
• 化学式: C₂₉H₅₂O₄
• 分子量: 464.729
• InChiKey: XDQCPSRLAXARDP-JPOBPWGRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.18
• 重原子数：
  33.0
• 可旋转键数：
  7.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  58.92
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 作用下， 生成 3β.5-dihydroxy-5β-cholestanone-(6)-dimethylacetal
  参考文献：
  名称：

  α-羟基酮向内酯的光化学重排

  摘要：

  通过Pyrex对3β-乙酰氧基-5α-羟基胆甾烷-6-一（I; R = Ac）和5β-顶基（VI; R = Ac）进行Uv辐照，得到3β-乙酰氧基-5α-羟基-5,6-巯基胆甾醇。 -6 -oic内酯（II; R = Ac）及其5β-顶基，几乎定量收率。所衍生的3-氧代-内酯被充分平衡以利于反式异构体（VIII）。在O-氘代乙醇中的O-氘代化合物（I和VI； R = Ac）进行光异构化时，氘原子仅以一种构型在C-7掺入。因此，整个重排是立体定向的。

  DOI：

  10.1039/j39680002494

文献信息

• Willingness to pay for publicly-financed health care: how should we use the numbers?
  作者：Phil Shackley、Cam Donaldson

  DOI：10.1080/00036840050155940

  日期：2000.12.1

  This paper addresses the question of how willingness to pay (WTP) values in health care evaluation can be used by policy makers. The way in which WTP values are used depends on from whom values are elicited and whether the good concerned is privately-financed or publicly-financed through taxation. Thus, four possible uses of WTP values are identified. The focus is on the two uses which arise in the publicly-financed situation. 'Conventional' use of WTP values, where the decision as to whether or not to provide a service depends upon whether or not WTP values are greater than total cost, applies only in the privately-financed, and not publicly-financed situations. The situations with publicly-financed goods are more complex. The use of WTP values for publicly-financed goods is justified and illustrated.