N-(5-((2-cyclohexylethyl)amino)-10-methyl-9H-benzo[a]phenoxazin-9-ylidene) ethanaminium chloride | 1467077-57-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 菲咯啉
• 英文名称: N-(5-((2-cyclohexylethyl)amino)-10-methyl-9H-benzo[a]phenoxazin-9-ylidene) ethanaminium chloride
• CAS: 1467077-57-1
• 化学式: C₂₇H₃₁N₃O*ClH
• 分子量: 450.024
• InChiKey: RTJCTOKSVWFQKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.12
• 重原子数：
  32.0
• 可旋转键数：
  5.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  50.42
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  5-(ethylamino)-4-methyl-2-nitrosophenol hydrochloride 、 N-(2-cyclohexylethyl)naphthalen-1-amine 在 盐酸 作用下， 以 乙醇 、 水 为溶剂， 反应 1.5h， 以93%的产率得到N-(5-((2-cyclohexylethyl)amino)-10-methyl-9H-benzo[a]phenoxazin-9-ylidene) ethanaminium chloride
  参考文献：
  名称：

  Ultrasound promoted synthesis of Nile Blue derivatives

  摘要：

  Ultrasound irradiation was used for the first time towards the synthesis of new Nile Blue related benzo[a]phenoxazinium chlorides possessing isopentylamino, (2-cyclohexylethyl)amino and phenethylamino groups at 5-position of the heterocyclic system. The efficacy of sonochemistry was investigated with some of our earlier reported synthesis of benzo[a]phenoxazinium chlorides. This newer protocol proved competent in terms of reaction times and enhanced yields. Photophysical studies carried out in ethanol, water and simulated physiological conditions, revealed that emission maxima occurred in the range 644-656 nm, with high fluorescent quantum yields. Other attractive feature exhibited by these materials includes good thermal stability. These properties might be useful in the development of fluorescent probes for biotechnology. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ultsonch.2013.05.010