1-Cyclohexyl-2,2-dimethylpropan-1-amine | 1178669-47-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-Cyclohexyl-2,2-dimethylpropan-1-amine
• CAS: 1178669-47-0
• 化学式: C₁₁H₂₃N
• 分子量: 169.31
• InChiKey: FBFIDWJRFIMSLL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• PROCESS FOR PREPARING UNSYMMETRIC SECONDARY TERT-BUTYLAMINES IN THE LIQUID PHASE
  申请人：WIGBERS Christof Wilhelm

  公开号：US20110251433A1

  公开（公告）日：2011-10-13

  The present application relates to a process for preparing unsymmetric secondary tert-butylamines which, as well as the tert-butyl radical, also comprise an alkyl, cycloalkyl or benzyl radical. They are prepared by reacting corresponding aldehydes with tert-butylamine and hydrogen in the presence of hydrogenation catalysts (reductive amination) in the liquid phase.

  本申请涉及一种制备非对称次叔丁基胺的方法，这些胺除了叔丁基自由基外，还包括一个烷基、环烷基或苄基自由基。它们是通过在液相中在氢化催化剂（还原胺化）存在下，将相应的醛与叔丁胺和氢气反应制备而成的。
• VERFAHREN ZUR HERSTELLUNG VON UNSYMMETRISCHEN SEKUNDÄREN TERT-BUTYLAMINEN IN DER FLÜSSIGPHASE
  申请人：BASF SE

  公开号：EP2556046A1

  公开（公告）日：2013-02-13
• Quinoline-Based Kinase Inhibitors
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20160332985A1

  公开（公告）日：2016-11-17

  The present disclosure is generally directed to compounds of formula (I) which can inhibit AAKI (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAKI.
• QUINAZOLINE-BASED KINASE INHIBITORS
  申请人：Bristol-Myers Squibb Company

  公开号：US20170239249A1

  公开（公告）日：2017-08-24

  The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
• US8445726B2
  申请人：——

  公开号：US8445726B2

  公开（公告）日：2013-05-21