N-butyl-4-(N-methyl-2-hydroxyethyl amino)-1,8-naphthalimide | 1430411-65-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: N-butyl-4-(N-methyl-2-hydroxyethyl amino)-1,8-naphthalimide
• CAS: 1430411-65-6
• 化学式: C₁₉H₂₂N₂O₃
• 分子量: 326.395
• InChiKey: ZFCOYYKKJSJFPB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.66
• 重原子数：
  24.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  60.85
• 氢给体数：
  1.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  N-butyl-4-(N-methyl-2-hydroxyethyl amino)-1,8-naphthalimide 在 三溴化磷 、 三乙胺 作用下， 以 二氯甲烷 、 乙二醇甲醚 为溶剂， 反应 1.0h， 生成 2-butyl-6-[methyl-[2-(N-methylanilino)ethyl]amino]benzo[de]isoquinoline-1,3-dione
  参考文献：
  名称：

  Rational design of fluorescent viscosity sensors by the principle of photoinduced electron transfer

  摘要：

  To establish a new strategy for the development of fluorescent viscosity sensors by the principle of photoinduced electron transfer, three 4-aminonaphthalimide based D-(CH2)(2)-A molecules were designed and synthesized. The effects of solvent polarity and viscosity on the fluorescence spectra of these compounds were investigated. These compounds exhibit viscosity-sensitive fluorescence spectra in ethylene glycol-glycerol mixtures. A mechanism about exciplex formation was proposed to explain their viscosity sensitivity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.02.111
• 作为产物：
  描述：

  N-甲基-2-羟基乙胺 、 4-bromo-N-butylnaphthalimide 在 三乙胺 作用下， 以 乙二醇甲醚 为溶剂， 反应 4.0h， 以70%的产率得到N-butyl-4-(N-methyl-2-hydroxyethyl amino)-1,8-naphthalimide
  参考文献：
  名称：

  Rational design of fluorescent viscosity sensors by the principle of photoinduced electron transfer

  摘要：

  To establish a new strategy for the development of fluorescent viscosity sensors by the principle of photoinduced electron transfer, three 4-aminonaphthalimide based D-(CH2)(2)-A molecules were designed and synthesized. The effects of solvent polarity and viscosity on the fluorescence spectra of these compounds were investigated. These compounds exhibit viscosity-sensitive fluorescence spectra in ethylene glycol-glycerol mixtures. A mechanism about exciplex formation was proposed to explain their viscosity sensitivity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.02.111