(11I(2),16I+/-)-9-Fluoro-11,17-dihydroxy-21-[(2-hydroxyacetyl)oxy]-16-methylpregna-1,4-diene-3,20-dione | 930105-28-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (11I(2),16I+/-)-9-Fluoro-11,17-dihydroxy-21-[(2-hydroxyacetyl)oxy]-16-methylpregna-1,4-diene-3,20-dione
• 英文别名: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2-hydroxyacetate
• CAS: 930105-28-5
• 化学式: C₂₄H₃₁FO₇
• 分子量: 450.5
• InChiKey: MNXXGOJDFJELEU-LVYMPEDWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  121
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• DRUG RELEASE COMPOSITIONS AND METHODS FOR DELIVERY
  申请人：ABBOTT DIABETES CARE INC.

  公开号：US20220202322A1

  公开（公告）日：2022-06-30

  The present disclosure provides therapeutic compositions and methods for delivering a therapeutic agent in close proximity to an analyte sensor. In certain embodiments, the present disclosure provides analyte sensors including one or more therapeutic agents, e.g., covalently-bound therapeutic agents. In certain embodiments, the present disclosure further provides therapeutic releasing compositions and methods of delivering such therapeutic releasing compositions.
• [EN] AN ANALYTE SENSOR AND SHARP FOR DELIVERING A THERAPEUTIC AGENT IN CLOSE PROXIMITY TO AN ANALYTE SENSOR AND METHODS THEREFORE<br/>[FR] CAPTEUR D'ANALYTE ET EMBOUT POINTU POUR L'ADMINISTRATION D'UN AGENT THÉRAPEUTIQUE À PROXIMITÉ IMMÉDIATE D'UN CAPTEUR D'ANALYTE ET MÉTHODES ASSOCIÉES
  申请人：[en]ABBOTT DIABETES CARE INC.

  公开号：WO2022147512A1

  公开（公告）日：2022-07-07

  The present disclosure provides therapeutic compositions and methods for delivering a therapeutic agent in close proximity to an analyte sensor. In certain embodiments, the present disclosure provides analyte sensors including one or more therapeutic agents, e.g, covalently-bound therapeutic agents. In certain embodiments, the present disclosure further provides therapeutic releasing compositions and methods of delivering such therapeutic releasing compositions.