5-chloro-7-iodoquinolin-8-ol;[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate | 52932-94-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 5-chloro-7-iodoquinolin-8-ol;[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate
• CAS: 52932-94-2
• 化学式: C36H41ClF2INO7
• 分子量: 800.1
• InChiKey: CVUQAAZGOGWDCF-BFBJLMMVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.64
• 重原子数：
  48
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  134
• 氢给体数：
  3
• 氢受体数：
  10

文献信息

• Methods and systems of delivering medication via inhalation
  申请人：Next Safety, Inc.

  公开号：EP1911481A2

  公开（公告）日：2008-04-16

  Systems and methods for delivery of a drug to the respiratory system of a patient where the drug is supplied at a positive pressure relative to atmospheric pressure are provided. In particular, the drugs are delivered to the respiratory system of a patient who is capable of unassisted breathing. With the systems and methods of the present disclosure, medication available in a variety of forms is introduced in a controlled fashion into the air stream in aerosol, nebulized, or vaporized form.

  提供了向病人的呼吸系统输送药物的系统和方法，其中药物是在相对于大气压的正压下提供的。特别是，将药物输送到能够进行无助呼吸的患者的呼吸系统。利用本公开的系统和方法，可将各种形式的药物以气溶胶、雾化或汽化的形式有控制地引入气流中。
• ZUSAMMENSETZUNG ZUR TOPISCHEN BEHANDLUNG VON NICHT-MIKROORGANISMUS-VERURSACHTEN ENTZÜNDLICHEN HAUT- UND SCHLEIMHAUTERKRANKUNGEN
  申请人：Bläss, Markus

  公开号：EP3675814A1

  公开（公告）日：2020-07-08
• METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION
  申请人：LeMahieu Edward

  公开号：US20080066739A1

  公开（公告）日：2008-03-20

  Systems and methods for delivery of a drug to the respiratory system of a patient where the drug is supplied at a positive pressure relative to atmospheric pressure are provided. In particular, the drugs are delivered to the respiratory system of a patient who is capable of unassisted breathing. With the systems and methods of the present disclosure, medication available in a variety of forms is introduced in a controlled fashion into the air stream in aerosol, nebulized, or vaporized form.