5-(1,4,7,10-tetrathia-13-aza-cyclopentadec-13-yl)-naphthalene-1-sulfonyl chloride | 1436859-18-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-(1,4,7,10-tetrathia-13-aza-cyclopentadec-13-yl)-naphthalene-1-sulfonyl chloride
• 英文别名: 5-(1,4,7,10-Tetrathia-13-azacyclopentadec-13-yl)naphthalene-1-sulfonyl chloride
• CAS: 1436859-18-5
• 化学式: C₂₀H₂₆ClNO₂S₅
• 分子量: 508.215
• InChiKey: SRNGSQCRMDSPKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  29
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  147
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  硅烷偶联剂 KH-540 、 5-(1,4,7,10-tetrathia-13-aza-cyclopentadec-13-yl)-naphthalene-1-sulfonyl chloride 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以68%的产率得到5-(1,4,7,10-tetrathia-13-azacyclopentadec-13-yl)-N-(3-triethoxysilylpropyl)naphthalene-1-sulfonamide
  参考文献：
  名称：

  Azathia crown ether possessing a dansyl fluorophore moiety functionalized silica nanoparticles as hybrid material for mercury detection in aqueous medium

  摘要：

  A novel fluorescent hybrid material for Hg2+ detection using a derivative of dansyl fluorophore with azathia crown ether moiety grafted on silica nanoparticles (SiNPs) was prepared and characterized. The designed nanosensor exhibited pronounced Hg2+ selective ON-OFF type fluorescence switching upon binding. The presence of other metal ions has no observable effect on the sensitivity and selectivity of the prepared nanosensor toward the Hg2+ anions. The new nanosensor provided highly selective sensing to Hg2+) in EtOH/water solvent mixtures (pH=7) with a detection limit of 10(-7) M. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.04.072
• 作为产物：
  描述：

  5-氯萘-1-磺酰氯 在 三聚氯氰 、 18-冠醚-6 、 三乙胺 、 sodium hydroxide 作用下， 以 丙酮 、 乙腈 为溶剂， 反应 38.83h， 生成 5-(1,4,7,10-tetrathia-13-aza-cyclopentadec-13-yl)-naphthalene-1-sulfonyl chloride
  参考文献：
  名称：

  Azathia crown ether possessing a dansyl fluorophore moiety functionalized silica nanoparticles as hybrid material for mercury detection in aqueous medium

  摘要：

  A novel fluorescent hybrid material for Hg2+ detection using a derivative of dansyl fluorophore with azathia crown ether moiety grafted on silica nanoparticles (SiNPs) was prepared and characterized. The designed nanosensor exhibited pronounced Hg2+ selective ON-OFF type fluorescence switching upon binding. The presence of other metal ions has no observable effect on the sensitivity and selectivity of the prepared nanosensor toward the Hg2+ anions. The new nanosensor provided highly selective sensing to Hg2+) in EtOH/water solvent mixtures (pH=7) with a detection limit of 10(-7) M. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.04.072