N-(1-ethyl-1H-pyrazol-3-yl)acetamide | 1694042-71-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(1-ethyl-1H-pyrazol-3-yl)acetamide
• 英文别名: N-(1-ethylpyrazol-3-yl)acetamide
• CAS: 1694042-71-1
• 化学式: C₇H₁₁N₃O
• 分子量: 153.18
• InChiKey: XUQBBXUXOGOWMK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  46.9
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] BENZIMIDAZOLE DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS DE BENZIMIDAZOLE ET LEURS UTILISATIONS
  申请人：PELOTON THERAPEUTICS INC

  公开号：WO2015175845A1

  公开（公告）日：2015-11-19

  Benzimidazole derivatives of Formula I, that modulate the activity of ACSS2 are disclosed for therapeutic use. The fused imidazole ring of the compounds disclosed has a diarylmethyl or diarylmethanol moiety attached at the 2-position and the compounds have at least one other substituent at the 5 or 6 position of the benzimidazole. Also disclosed are methods of using the benzimidazole compounds for the treatment of diseases or disorders, such as cancer.

  公开了公式I的苯并咪唑衍生物，其调节ACSS2的活性，用于治疗。所公开的化合物的融合咪唑环在2位上连接有二芳基甲基或二芳基甲醇基团，并且这些化合物在苯并咪唑的5位或6位至少有另一个取代基。还公开了使用苯并咪唑化合物治疗疾病或疾病的方法，如癌症。
• N-PYRAZOLYL CARBOXAMIDES AS CRAC CHANNEL INIHIBITORS
  申请人：Allen David George

  公开号：US20120053150A1

  公开（公告）日：2012-03-01

  The present invention relates to amide compounds, processes for their preparation, pharmaceutical compositions containing these compounds and to their use in the treatment of disorders, conditions or disorders such as allergic disorders, inflammatory disorders and disorders of the immune system.

  本发明涉及酰胺化合物、其制备方法、含有这些化合物的药物组合物以及它们在治疗过敏性疾病、炎症性疾病和免疫系统疾病等疾病、症状或障碍中的应用。
• NOVEL EFFECTIVE ANTIVIRAL COMPOUNDS AND METHODS USING SAME
  申请人：THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

  公开号：US20170114060A1

  公开（公告）日：2017-04-27

  The present invention includes compounds that are useful in preventing or treating viral infections caused by an enveloped RNA virus, such as viral infections caused by a Filovirus, arenavirus, rhabdovirus, paramyxovirus, orthomyxovirus and/or retrovirus. The present invention further includes compositions comprising such compounds, and methods of treating a viral infection in a subject using such compounds.
• US8399436B2
  申请人：——

  公开号：US8399436B2

  公开（公告）日：2013-03-19