| 865981-01-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• CAS: 865981-01-7
• 化学式: C₂₀H₂₀N₂
• 分子量: 288.392
• InChiKey: DFFJCTNJMWBIGA-WOJBJXKFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.54
• 重原子数：
  22.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  38.05
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  在 ammonium tetrafluoroborate 作用下， 生成
  参考文献：
  名称：

  Construction of a new type of chiral bidentate NHC ligands: copper-catalyzed asymmetric conjugate alkylation

  摘要：

  We synthesized in three steps simple chiral bidentate NHC Compounds that carry an achiral coordinating group as N-substituent and revealed that they serve as efficient chiral auxiliaries for the copper-catalyzed asymmetric conjugate addition of dialkylzinc to acyclic enones (up to 97% ee). (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.026
• 作为产物：
  描述：

  溴苯 、 (1R,2R)-1,2-二苯基乙二胺 在 palladium diacetate 、 R-(+)-1,1'-联萘-2,2'-双二苯膦 、 sodium t-butanolate 作用下， 生成
  参考文献：
  名称：

  Construction of a new type of chiral bidentate NHC ligands: copper-catalyzed asymmetric conjugate alkylation

  摘要：

  We synthesized in three steps simple chiral bidentate NHC Compounds that carry an achiral coordinating group as N-substituent and revealed that they serve as efficient chiral auxiliaries for the copper-catalyzed asymmetric conjugate addition of dialkylzinc to acyclic enones (up to 97% ee). (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.026