3β-acetoxy-5α-ergostatrien-(7.9(11).22t)-ol-(5) | 53286-59-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3β-acetoxy-5α-ergostatrien-(7.9(11).22t)-ol-(5)
• 英文别名: Essigsaeure-[5-hydroxy-5α-ergostatrien-(7.9(11).22t)-yl-(3β)-ester]；(10R)-5t-Hydroxy-3c-acetoxy-10r.13c-dimethyl-17c-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(14tH)-Δ^7.9(11)-dodecahydro-1H-cyclopenta[a]phenanthren；3β-Acetoxy-24β_F-methyl-5α-cholestatrien-(7.9(11).22t)-ol-(5)；[(3S,5R,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-5-hydroxy-10,13-dimethyl-1,2,3,4,6,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-yl] acetate
• CAS: 53286-59-2
• 化学式: C₃₀H₄₆O₃
• 分子量: 454.693
• InChiKey: UJZUPCLEQOADBH-JDBPENHISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3β-acetoxy-5α-ergostatrien-(7.9(11).22t)-ol-(5) 在 单过氧邻苯二甲酸 、 乙醚 、 氯仿 作用下， 生成 3β-acetoxy-5-hydroxy-5α,8α-ergosta-9(11),22t-dien-7-one
  参考文献：
  名称：

  Magnetic Resonance Imaging of Sexual Intercourse: Initial Experience

  摘要：

  The objective of this study was to investigate sexual intercourse with magnetic resonance imaging (MRI), A volunteer couple (30 year-old male, 27-year-old female) with a normal sex life, had face-to face sexual intercourse (reversed missionary position) under MRI Static and dynamic T2-weighted sagittal sequencies were acquired on the midline before and during vaginal penetration. In this position, before penetration, The vagina was parallel to the pubococygeal line and had normal anterior convevity. After penetration, accentuation of The vaginal convexity was observed, produced by the penile gland reaching the anterior cul-de-sac and contact With the a anterior vaginal wall. The posterior bladder wall was pushed forward and upward, the uterus upward and backward. In this initial experience, ive observed a preferential contact of the penis in erection with the anterior vaginal wall and the anterior cul-de-sac in the face-to-face sexual position. MRI allows a noninvasive assessment of sexual intercourse.

  DOI：

  10.1080/713846807
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 镍 、 乙酸乙酯 作用下， 生成 3β-acetoxy-5α-ergostatrien-(7.9(11).22t)-ol-(5)
  参考文献：
  名称：

  Bladon et al., Journal of the Chemical Society, 1952, p. 4883,4888

  摘要：

  DOI：

文献信息

• Laws, Journal of the Chemical Society, 1953, p. 4185
  作者：Laws

  DOI：——

  日期：——
• Windaus et al., Justus Liebigs Annalen der Chemie, 1930, vol. 477, p. 268,278
  作者：Windaus et al.

  DOI：——

  日期：——
• Elks et al., Journal of the Chemical Society, 1954, p. 451,459
  作者：Elks et al.

  DOI：——

  日期：——
• Bladon et al., Journal of the Chemical Society, 1953, p. 2916,2919
  作者：Bladon et al.

  DOI：——

  日期：——
• Inhoffen; Mengel, Chemische Berichte, 1954, vol. 87, p. 146,156
  作者：Inhoffen、Mengel

  DOI：——

  日期：——