3,4-Dihydroxy-5,5-dimethyl-5H-furan-2-one | 70728-33-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 英文名称: 3,4-Dihydroxy-5,5-dimethyl-5H-furan-2-one
• 英文别名: 3,4-Dihydroxy-5,5-dimethylfuran-2-one
• CAS: 70728-33-5
• 化学式: C₆H₈O₄
• 分子量: 144.127
• InChiKey: PUUXCQMVFRPAJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Solution phase homogeneous assays
  申请人：Beckman Coulter, Inc.

  公开号：US10036708B2

  公开（公告）日：2018-07-31

  Methods, reagents, kits and systems are disclosed for determining an analyte in a sample suspected of containing the analyte where all reagents are soluble in aqueous solution. One assay method includes treating a sample suspected of containing the analyte under conditions such that if the analyte is present, an activator is brought into reactive configuration with a chemiluminescent compound to activates it. The sample is also treated with an agent to reduce signal not related to analyte. Finally, the sample is treated with a trigger solution thereby producing light from the activated chemiluminescent compound. No reagents are associated with a surface or other solid phase.

  本发明公开了用于测定疑似含有分析物的样品中分析物的方法、试剂、试剂盒和系统，其中所有试剂均可溶于水溶液。一种检测方法包括处理疑似含有被分析物的样品，如果样品中存在被分析物，则将活化剂与化学发光化合物反应配置，使其活化。还用一种药剂处理样品，以减少与分析物无关的信号。最后，用触发溶液处理样品，从而使活化的化学发光化合物发光。试剂与表面或其他固相无关。
• Specific binding chemiluminescent assay
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US11320424B2

  公开（公告）日：2022-05-03

  Method of assaying for an analyte in a sample, and kits for performing the assay.

  化验样品中分析物的方法，以及进行化验的试剂盒。
• SOLUTION PHASE HOMOGENEOUS ASSAYS
  申请人：Beckman Coulter, Inc.

  公开号：EP2401392B1

  公开（公告）日：2017-01-25
• SPECIFIC BINDING CHEMILUMINESCENT ASSAY
  申请人：3M Innovative Properties Company

  公开号：EP3821249B1

  公开（公告）日：2022-06-29
• NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS
  申请人：AKHAVAN-TAFTI Hashem

  公开号：US20100273189A1

  公开（公告）日：2010-10-28

  Methods, reagents, kits and systems are disclosed for determining an analyte in a sample, the assay method comprising forming a reaction mixture in an aqueous solution, by adding a chemiluminescent-labeled immobilized specific binding member, an activator-labeled specific binding member, a selective signal inhibiting agent, and a sample, wherein the chemiluminescent-labeled immobilized specific binding member and activator-labeled specific binding member bind to analyte present in the sample to form a binding complex, and adding to the reaction mixture a trigger solution to release a detectable chemiluminescent signal correlated to the amount of the analyte-bound binding complex present in the reaction mixture.