N-Boc-L-trans-Pro(4-<4-<(E)-2-(4-cyanophenyl)-1-diazenyl>phenoxy>)-OMe | 244786-53-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: N-Boc-L-trans-Pro(4-<4-<(E)-2-(4-cyanophenyl)-1-diazenyl>phenoxy>)-OMe
• CAS: 244786-53-6
• 化学式: C₂₄H₂₆N₄O₅
• 分子量: 450.494
• InChiKey: BXGIDKHVXUPMNM-HEMCCEMMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  33.0
• 可旋转键数：
  5.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  113.58
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  N-Boc-L-trans-Pro(4-<4-<(E)-2-(4-cyanophenyl)-1-diazenyl>phenoxy>)-OMe 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 1.5h， 生成
  参考文献：
  名称：

  A Remarkably Efficient Azobenzene Peptide for Holographic Information Storage

  摘要：

  A new family of proline-based azobenzene peptides (DNO) for holographic information storage is reported.:By use of polarization holography, it was found that gratings with extraordinarily high diffraction efficiency (up to 80%) can be recorded in hundreds of milliseconds in a similar to 13-mu m-thick film of dimer 10. This represents a decrease of the response time by more than 2 orders of magnitude when compared to that of the ornithine-based DNO dimer previously reported. Furthermore, it supports the expectation that increasing the rigidity of the peptide backbone is: crucial in the design of effective azobenzene peptides for optical recording. Gratings recorded in 10 can be erased-by circularly polarized light in a few-seconds. It is also noted that, unlike DNOs previously reported, 10 is soluble in common organic solvents and can be assembled by solution phase synthesis, which is mandatory for large-scale fabrication.

  DOI：

  10.1021/ja981402y
• 作为产物：
  描述：

  苯酚 、 alkaline earth salt of/the/ methylsulfuric acid 在 盐酸 、 sodium hydroxide 、 三苯基膦 、 sodium nitrite 、 偶氮二甲酸二乙酯 作用下， 以 四氢呋喃 为溶剂， 反应 33.0h， 生成 N-Boc-L-trans-Pro(4-<4-<(E)-2-(4-cyanophenyl)-1-diazenyl>phenoxy>)-OMe
  参考文献：
  名称：

  A Remarkably Efficient Azobenzene Peptide for Holographic Information Storage

  摘要：

  A new family of proline-based azobenzene peptides (DNO) for holographic information storage is reported.:By use of polarization holography, it was found that gratings with extraordinarily high diffraction efficiency (up to 80%) can be recorded in hundreds of milliseconds in a similar to 13-mu m-thick film of dimer 10. This represents a decrease of the response time by more than 2 orders of magnitude when compared to that of the ornithine-based DNO dimer previously reported. Furthermore, it supports the expectation that increasing the rigidity of the peptide backbone is: crucial in the design of effective azobenzene peptides for optical recording. Gratings recorded in 10 can be erased-by circularly polarized light in a few-seconds. It is also noted that, unlike DNOs previously reported, 10 is soluble in common organic solvents and can be assembled by solution phase synthesis, which is mandatory for large-scale fabrication.

  DOI：

  10.1021/ja981402y