3-[[6-(7,7-dimethyl-6,8-dihydro-5H-quinazolin-2-yl)pyridin-2-yl]methyl]benzonitrile | 1373153-17-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-[[6-(7,7-dimethyl-6,8-dihydro-5H-quinazolin-2-yl)pyridin-2-yl]methyl]benzonitrile
• CAS: 1373153-17-3
• 化学式: C₂₃H₂₂N₄
• 分子量: 354.454
• InChiKey: VTZRYZTUSOFZGJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  62.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] NOVEL MICROBICIDES<br/>[FR] NOUVEAUX MICROBICIDES
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2012056003A1

  公开（公告）日：2012-05-03

  Compounds of formula (I), wherein G represents together with the two carbon atoms of the pyrimidine ring to which it is attached, a 5- to 7-membered aliphatic carbocyclic or heterocyclic ring system which contain 0 to 2 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur; and wherein said 5- to 7-membered aliphatic carbocyclic or heterocyclic ring system can be mono-, di- or trisubstituted by substituents selected from the group consisting of halogen, keto, C1-C6alkyl, C1-C6alkoxy, C1-C6alkyloximino and C1-C6alkylendioxy; and wherein the other substituents R1, R2, R3, R4, R5 and R6 are as defined in claim 1, and their use as microbicides.

  式（I）的化合物，其中G代表与其连接的嘧啶环的两个碳原子一起，含有0至2个来自氮、氧和硫组成的杂原子的5至7元杂原子的脂环或杂环系统；其中所述的5至7元脂环或杂环系统可以通过来自卤素、酮基、C1-C6烷基、C1-C6烷氧基、C1-C6烷氧基亚胺和C1-C6烷基二氧基的取代基进行单取代、双取代或三取代；以及其他取代基R1、R2、R3、R4、R5和R6如权利要求1所定义，并且它们作为微生物杀菌剂的用途。
• NOVEL MICROBICIDES
  申请人：Trah Stephan

  公开号：US20130281467A1

  公开（公告）日：2013-10-24

  Compounds of formula (I), wherein G represents together with the two carbon atoms of the pyrimidine ring to which it is attached, a 5- to 7-membered aliphatic carbocyclic or heterocyclic ring system which contain 0 to 2 heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur; and wherein said 5- to 7-membered aliphatic carbocyclic or heterocyclic ring system can be mono-, di- or trisubstituted by substituents selected from the group consisting of halogen, keto, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 alkyloximino and C 1 -C 6 alkylendioxy; and wherein the other substituents R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are as defined in claim 1 , and their use as microbicides.

  式(I)的化合物，其中G与其所连接的嘧啶环的两个碳原子一起表示5-至7-成员的脂肪环烷基或杂环烷基环系统，该环系统中包含0至2个选自氮、氧和硫的杂原子; 且所述的5-至7-成员的脂肪环烷基或杂环烷基环系统可以被取代基选自卤素、酮、C1-C6烷基、C1-C6烷氧基、C1-C6烷氧肟基和C1-C6烷基二氧基取代，且其他取代基R1、R2、R3、R4、R5和R6如权利要求1所定义，并且它们的用途是作为微生物杀灭剂。