((furan-2-yl)methyl)(2-(thiophen-2-yl)ethyl)amine | 86052-45-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: ((furan-2-yl)methyl)(2-(thiophen-2-yl)ethyl)amine
• 英文别名: N-Furfuryl-2-(2-thienyl)ethanamine；N-(furan-2-ylmethyl)-2-thiophen-2-ylethanamine
• CAS: 86052-45-1
• 化学式: C₁₁H₁₃NOS
• mdl: MFCD11145553
• 分子量: 207.296
• InChiKey: TWRNUPARUWYOEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.272
• 拓扑面积：
  53.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  ((furan-2-yl)methyl)(2-(thiophen-2-yl)ethyl)amine 以 乙醇 、 水 为溶剂， 生成 [Zn((furan-2-yl)methyl(2-(thiophen-2-yl)ethyl)dithiocarbamate)₂]
  参考文献：
  名称：

  Synthesis and characterization of Ni(II) and Zn(II) complexes of (furan-2-yl)methyl(2-(thiophen-2-yl)ethyl)dithiocarbamate (ftpedtc): X-ray structures of [Zn(ftpedtc)2(py)] and [Zn(ftpedtc)Cl(1,10-phen)]

  摘要：

  Seven complexes of a new dithiocarbamate ligand (ftpedtc = (furan-2-yl)methyl(2-(thiophen-2-yl)ethyl)dithiocarbamate) namely [Ni(ftpedtc)(21) (1), [Ni(ftpedtc)(NCS)(PPh3)] (2), [Ni(ftpedtc)(PPh3)(2)]C-104 (3), [Zn(ftpedtc)2] (4), [zn(ftpedtc)2(PY)1 (5), [Zn(ftpedtc)2(1,10-phen)1 (6) and [Zn(ftpedtc)2(2,2'-bipYl (7) have been prepared. The complexes were characterized by IR, UV-Vis and NMR (1H and 13C) spectroscopy. Single crystal X-ray structural analysis was carried out for complexes 5 and [Zn(ftpedtc)C1(1,10-phen)] (8). Electronic spectral studies suggest square planar geometry for nickel complexes. The 13C NMR peaks of the group N13CS2 are found in all the cases, at around 205.0 ppm, which indicates the bidentate character of the dithiocarbamate ligand. X-ray structures of 5 and 8 show bidentate coordination by dithiocarbamate ligands and a distorted trigonal bipyramidal geometry for zinc, defined by NS4 and C1N2S2 donor sets, respectively. The packing in 8 involves 7t-7C stacking interactions involving the 1,10-phenanthroline ring systems with the distance between ring centroids being 3.587 A (C) 2014 ElseVier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2014.09.019
• 作为产物：
  描述：

  噻吩乙胺 在 sodium tetrahydroborate 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 14.0h， 生成 ((furan-2-yl)methyl)(2-(thiophen-2-yl)ethyl)amine
  参考文献：
  名称：

  含苄基和糠基的Pb（II）二硫代氨基甲酸酯配合物的合成和光谱研究及其作为PbS纳米粒子的前体的用途。

  摘要：

  已经制备了基于苄基和糠基的九种双（二硫代氨基甲酸酯）铅配合物。使用IR和NMR光谱对复合物进行表征。所有配合物在与二硫代氨基甲酸酯配体相关的（1）H和（13）C NMR光谱中均显示出预期的信号。IR和（13）C NMR光谱研究表明，S（2）CN双键特征随与氮原子相连的烷基链长度的增加而增加。双（N-苄基-N-（2-苯乙基）二硫代氨基甲酸酯-S，S'）铅（II）（3）和双（N-糠基-N-（2-苯乙基）二硫代氨基甲酸酯-S，S'）铅（ II）（4）已用作合成乙二胺封端的PbS纳米粒子的单一来源前体。粉末X射线衍射（PXRD），扫描电子显微镜（SEM），FTIR，紫外可见光谱和荧光光谱已被用于表征所制备的硫化铅纳米颗粒。PXRD测量表明，PbS纳米粒子是具有面心立方结构的单相。

  DOI：

  10.1016/j.saa.2012.06.052

文献信息

• PO-Activated Olefination and Conversion of Aldehydes and Ketones to Higher Amines; II. Synthesis of Arylethylamines
  作者：A. Heymes、I. Chekroun

  DOI：10.1055/s-1987-27902

  日期：——

  The transformation of arylcarboxaldehydes and/or - ketones 2 by three different routes into arylethylamines 3 and/or 4 is reported. According to the first route, the intermediate iminophosphonates 9 react through a classical PO-activated olefination. The second and the third involve the rearrangement of the iminophosphonates 9 into the vinylphosphoramidates 12.

  我们报道了通过三条不同路线将芳基羧醛和/或酮 2 转化为芳基乙胺 3 和/或 4。根据第一条路线，中间体亚胺膦酸盐 9 通过经典的 PO 活化烯化反应。第二条和第三条路线涉及亚胺膦酸盐 9 重排为乙烯基膦酸酰胺 12。
• Synthesis, spectral and X-ray structural studies on Hg(II) dithiocarbamate complexes: A new precursor for HgS nanoparticles
  作者：Sajad Hussain Dar、S. Thirumaran、S. Selvanayagam

  DOI：10.1016/j.poly.2015.04.020

  日期：2015.8

  Bis(N-furfuryl-N-(2-phenylethyl)dithiocarbamato-S,S')mercury(II) (1), bis((furan-2-yl)methyl(2-(thiophen-2-yl)ethyl)dithiocarbamato-S,S')mercury(II) (2), bis(N-benzyl-N-(2-(thiophen-2-yl)ethyl)dithiocarbarnato-S,S')mercury(II) (3) and bis(N-furfuryl-N-propyldithiocarbamato-S,S')mercury(II) (4) have been prepared and characterized by IR and NMR spectroscopy. Compounds 1 and 2 have also been characterized by the X-ray diffraction technique. In complexes 1 and 2, the metal centres are five and four coordinated, respectively. The coordination geometry of 1 is intermediate between a square pyramidal and trigonal bipyramidal coordination polyhedron, with tau(5) = 0.53. Hg(II) is in a distorted [HgS4] tetrahedral environment in compound 2. This difference in geometry between complexes 1 and 2 is probably due to the effect of the N-bound organic moiety of the dithiocarbamate ligand and the crystal packing. The crystal structures show the presence of C-H...S interactions. Complex 2 has been dissolved in ethylenediamine and refluxed for 15 mm and 1 h to yield ethylenediamine capped mercury sulfide and mercury sulfide without a capping agent (en), respectively. The resulting nanoparticles have been characterized by powder X-ray diffraction (PXRD), SEM, EDAX, IR, UV-Vis and fluorescence spectroscopy. The powder Xray diffraction data confirm the particles to be very crystalline with the alpha phase (cinnabar) present in both samples. (C) 2015 Elsevier Ltd. All rights reserved.
• Procédé de préparation de dérivés des (thiényl-2)- et (thiényl-3)-2 éthylamines et produits ainsi obtenus
  申请人：ELF SANOFI

  公开号：EP0068979B1

  公开（公告）日：1985-09-25