4-Phenyl-5-(p-tolyl)-3-oxazolin | 36879-73-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 4-Phenyl-5-(p-tolyl)-3-oxazolin
• 英文别名: 4-phenyl-5-p-tolyl-2,5-dihydro-oxazole；Oxazole, 2,5-dihydro-5-(4-methylphenyl)-4-phenyl-；5-(4-methylphenyl)-4-phenyl-2,5-dihydro-1,3-oxazole
• CAS: 36879-73-9
• 化学式: C₁₆H₁₅NO
• 分子量: 237.301
• InChiKey: ZOLOZUSFYXBCHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  21.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  对甲基苯甲醛 、 3-phenyl-2H-azirine 以 苯 为溶剂， 反应 6.0h， 生成 4-Phenyl-5-(p-tolyl)-3-oxazolin
  参考文献：
  名称：

  3-苯基-2 h环叠氮基苯丙氨酸的光化学环加成反应。31.摄影展†

  摘要：

  关于3-苯基2的光化学缩合实验ħ -azirines 1与脂肪族和芳香族醛-3-恶唑啉4中充分描述（CF。方案1）。首先形成光化学类型为2的腈亚甲基，然后以区域特异性方式非常快速地与醛进行热反应，生成3-恶唑啉4。在位置2（l b和1 c）上单取代的嗪生成顺式，反-恶唑啉异构体的混合物，其中顺式异构体占主导地位。环加成反应的立体选择性可以通过简单的模型来合理化（方案10）。

  DOI：

  10.1002/hlca.19730560745

文献信息

• Sweetener and flavor compositions, methods of making and methods of use thereof
  申请人：EPC Natural Products Co., Ltd.

  公开号：US11147295B2

  公开（公告）日：2021-10-19

  Sweetener and flavor compositions with improved taste profiles are disclosed. Also disclosed are methods of making and methods of using such sweetener and flavor compositions.

  本发明公开了具有改进口味特征的甜味剂和香料组合物。还公开了制作和使用这种甜味剂和香料组合物的方法。
• Tasteful natural sweetener and flavor
  申请人：EPC Natural Products Co., Ltd.

  公开号：US11154079B2

  公开（公告）日：2021-10-26

  The invention describes products, uses thereof, compositions thereof, and methods to prepare products formed from Maillard reaction products from a sugar donor and/or sweet tea extracts, stevia extracts, swingle (mogroside) extracts, one or more sweet tea extract components, one or more steviol glycosides, one or more mogrosides, one or more glycosylated sweet tea glycosides, one or more glycosylated steviol glycosides or one or more glycosylated mogrosides and an amine donor/reactant.

  本发明描述了由糖供体和/或甜茶提取物、甜叶菊提取物、秋茄（mogroside）提取物、一种或多种甜茶提取物成分、一种或多种甜菊醇苷、一种或多种mogrosides、一种或多种糖基化甜茶苷、一种或多种糖基化甜菊醇苷或一种或多种糖基化mogrosides和胺供体/反应物的Maillard反应产物形成的产品、其用途、其组合物和制备方法。
• SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF
  申请人：EPC Natural Products Co., Ltd.

  公开号：EP3790407A1

  公开（公告）日：2021-03-17
• TASTEFUL NATURAL SWEETENER AND FLAVOR
  申请人：EPC Natural Products Co., Ltd.

  公开号：US20200029607A1

  公开（公告）日：2020-01-30

  The invention describes products, uses thereof, compositions thereof, and methods to prepare products formed from Maillard reaction products from a sugar donor and/or sweet tea extracts, stevia extracts, swingle (mogroside) extracts, one or more sweet tea extract components, one or more steviol glycosides, one or more mogrosides, one or more glycosylated sweet tea glycosides, one or more glycosylated steviol glycosides or one or more glycosylated mogrosides and an amine donor/reactant.
• [EN] SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF<br/>[FR] COMPOSITIONS D'ÉDULCORANT ET D'ARÔME, LEURS PROCÉDÉS DE FABRICATION ET LEURS PROCÉDÉS D'UTILISATION
  申请人：EPC NATURAL PRODUCTS CO LTD

  公开号：WO2019217312A1

  公开（公告）日：2019-11-14

  Sweetener and flavor compositions with improved taste profiles are disclosed. Also disclosed are methods of making and methods of using such sweetener and flavor compositions.