bis(β,β,β-trichloro-α-hydroxyethyl)(o-hydroxyphenyl)phosphine | 133859-81-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: bis(β,β,β-trichloro-α-hydroxyethyl)(o-hydroxyphenyl)phosphine
• 英文别名: Bis(beta,beta,beta-trichloro-alpha-hydroxyethyl)(o-hydroxyphenyl)phosphine；2-bis(2,2,2-trichloro-1-hydroxyethyl)phosphanylphenol
• CAS: 133859-81-1
• 化学式: C₁₀H₉Cl₆O₃P
• 分子量: 420.871
• InChiKey: CYFASECMACSYQV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis(β,β,β-trichloro-α-hydroxyethyl)(o-hydroxyphenyl)phosphine 、 苯硼酸 以 苯 为溶剂， 以43%的产率得到(2-phenyl-4,6-bis(trichloromethyl)-5-o-hydroxyphenyl-1,3,2,5-dioxabora)phosphorinane
  参考文献：
  名称：

  Borylation of o-Hydroxyphenyl phosphorus derivatives

  摘要：

  The reactions of isobutyl diphenylborate with O,O-diethyl o-hydroxyphenylphosphonate and o-hydroxyphenylphosphine gave 5,6-benzo-2-phenyl-4-ethoxy-4-oxo-1,3,2,4-dioxaboraphosphorinane and o-diphenylboryloxyphenylphosphine, respectively. The borylation only at the alpha-hydroxyalkyl fragments of bis(beta,beta,beta-trichloro-alpha-hydroxyethyl)(o-hydroxyphenyl)phosphine and the conversion of the o-boryloxyphenyl phosphorus derivative to an alpha-boryloxyalkyl derivative upon the action of chloral indicates the greater stability of compounds with the P-C-O-B fragment than that for compounds with the P-C-C-O-B fragment.

  DOI：

  10.1007/bf00965441
• 作为产物：
  描述：

  邻羟基苯基膦 、 三氯乙醛 以 乙醚 为溶剂， 反应 1.0h， 以95%的产率得到bis(β,β,β-trichloro-α-hydroxyethyl)(o-hydroxyphenyl)phosphine
  参考文献：
  名称：

  Borylation of o-Hydroxyphenyl phosphorus derivatives

  摘要：

  The reactions of isobutyl diphenylborate with O,O-diethyl o-hydroxyphenylphosphonate and o-hydroxyphenylphosphine gave 5,6-benzo-2-phenyl-4-ethoxy-4-oxo-1,3,2,4-dioxaboraphosphorinane and o-diphenylboryloxyphenylphosphine, respectively. The borylation only at the alpha-hydroxyalkyl fragments of bis(beta,beta,beta-trichloro-alpha-hydroxyethyl)(o-hydroxyphenyl)phosphine and the conversion of the o-boryloxyphenyl phosphorus derivative to an alpha-boryloxyalkyl derivative upon the action of chloral indicates the greater stability of compounds with the P-C-O-B fragment than that for compounds with the P-C-C-O-B fragment.

  DOI：

  10.1007/bf00965441

文献信息

• BALUEVA, I. S.;NIKONOV, G. N.;VULFSON, S. G.;SARVAROVA, N. N.;ARBUZOV, B.+, IZV. AN CCCP. CEP. XIM.,(1991) N, S. 477-482
  作者：BALUEVA, I. S.、NIKONOV, G. N.、VULFSON, S. G.、SARVAROVA, N. N.、ARBUZOV, B.+

  DOI：——

  日期：——