4-ethyl-2,3,6-tribromo-phenol | 858240-70-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-ethyl-2,3,6-tribromo-phenol
• 英文别名: 2.3.5-Tribrom-4-hydroxy-1-aethyl-benzol；4-Aethyl-2,3,6-tribrom-phenol
• CAS: 858240-70-7
• 化学式: C₈H₇Br₃O
• 分子量: 358.855
• InChiKey: PEKOEDHNBBHDCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.24
• 重原子数：
  12.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  20.23
• 氢给体数：
  1.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  4-ethyl-2,3,6-tribromo-phenol 在 溴 作用下， 生成 2,3,6-tribromo-4-(1,2,2-tribromo-ethyl)-phenol
  参考文献：
  名称：

  Zincke; Siebert; Reinbach, Justus Liebigs Annalen der Chemie, 1902, vol. 322, p. 205

  摘要：

  DOI：
• 作为产物：
  描述：

  4-ethyl-2,3,6-tribromo-4-hydroxy-cyclohexa-2,5-dienone 生成 4-ethyl-2,3,6-tribromo-phenol
  参考文献：
  名称：

  Rural-Urban Differences in Health Risks, Resource Use and Expenditures Within Three State Medicaid Programs: Implications for Medicaid Managed Care

  摘要：

  This study uses Medicaid claims data for income‐eligible enrollees in California, Georgia and Mississippi to compare expenditures, resource usage and health risks between residents of rural and urban areas of the states. Resource use is measured using the Resource Based Relative Value Scale (RBRVS) system for professional services, hospital days and outpatient facility visits; it also is valued at private insurance reimbursement rates for the states. Health risks are measured using the diagnosis‐based Adjusted Clinical Group system. Resource use is compared on a risk‐adjusted basis with the use of urban Medicaid enrollees as the benchmark. We find that actual expenditures for rural care users are lower than for urban care users. However, because the proportion of Medicaid enrollees who use care is higher in rural than in urban areas in all three states, expenditures per rural enrollee are not consistently lower. Case mix is more resource intensive for rural compared to urban residents in all three states. Although resource usage is not systematically lower owerall for rural enrollees, on a risk‐adjusted basis they tend to use less hospital resources than urban enrollees. Capitation rates based on historical per enrollee expenditures would not appear to under‐reimburse managed care organizations for the care of rural as opposed to urban residents in the study states.

  DOI：

  10.1111/j.1748-0361.2002.tb00875.x

文献信息

• Zincke, Chemische Berichte, 1901, vol. 34, p. 256
  作者：Zincke

  DOI：——

  日期：——
• Cervical Cancer Risk as a Predictor of Pap Smear Use in Rural North Carolina
  作者：Mfon S. Cyrus-David、Robert Michielutte、Electra D. Paskett、Ralph D'Agostino、David Goff

  DOI：10.1111/j.1748-0361.2002.tb00878.x

  日期：2002.12

  Risk for invasive cervical cancer is reported to be higher in rural areas than urban ones, and cervical cancer‐related mortality is higher in rural women due to poorer utilization of preventive services and subsequent presentation at late stages of the disease. This cross‐sectional study examined the relationship between prevalence of risk factors for cervical cancer and the degree of compliance with risk‐appropriate screening guidelines for cervical cancer. Secondary data were analyzed for 614 women from Robeson County, NC, aged 40 and older, and of mainly rural and low socioeconomic status. High‐risk status was determined by the presence of any of the following five risk factors: a history of more than two sexual partners, age at first sexual intercourse under 18 years, history of sexually transmitted disease, history of sexually transmitted disease in sexual partner(s), and smoking. Low‐risk status was the absence of all factors. A high‐risk participant was considered compliant if she had had at least three Pap smears in the 3 years prior to the interview, while a low‐risk participant was considered compliant if she had had at least one Pap smear within the previous 3 years. Overall, 82% of the participants were at high risk for cervical cancer. However, only 41% of all participants were compliant with the risk‐appropriate screening guidelines. Low‐risk status was significantly associated with compliance with cervical cancer screening guidelines (adjusted OR = 6.7; 95% CI = 3.7 to 11.1, p = .0001). Findings in this study population suggest rural women at high risk for cervical cancer are less likely to be compliant with appropriate Pap smear screening guidelines, indicating the need to target educational programs.
• Zincke; Siebert; Reinbach, Justus Liebigs Annalen der Chemie, 1902, vol. 322, p. 186
  作者：Zincke、Siebert、Reinbach

  DOI：——

  日期：——