Me2SnClCH2CH(P(O)(OPr-i)2)2 | 127802-40-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: Me2SnClCH2CH(P(O)(OPr-i)2)2
• 英文别名: 2,2-Bis(diisopropoxyphosphoryl)ethyl-chloro-dimethyl-stannane；2,2-bis[di(propan-2-yloxy)phosphoryl]ethyl-chloro-dimethylstannane
• CAS: 127802-40-8
• 化学式: C₁₆H₃₇ClO₆P₂Sn
• 分子量: 541.577
• InChiKey: ZXNORKXIVGWHMF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  6.84
• 重原子数：
  26
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  Me2SnClCH2CH(P(O)(OPr-i)2)2 在 苯基溴化镁 作用下， 以 乙醚 为溶剂， 以90%的产率得到tetraisopropyl (2-(dimethyl(phenyl)stannyl)ethane-1,1-diyl)bis(phosphonate)
  参考文献：
  名称：

  2,2-Functionally disubstituted organotin compounds: synthesis and reactivity

  摘要：

  A series of 2,2-difunctional organotin compounds of the general type Me(3)SnCH(2)CHXY (X, Y = P(O)R(2) or C(O)R; R = (OPr)-Pr-i, OEt or Ph) has been synthesized by stannylmethylation of the appropriate 2,2-difunctional methanides Na[CHXY] with iodomethyl trimethylstannane. Derivatives with phenyl groups on tin cannot be made by this method. The reactions of the title compounds at the tin atom and at the acidic CH group of the bridging carbon atom and modifications of the functional P(O)R(2) and C(O)R groups are described.

  DOI：

  10.1016/0022-328x(94)88031-x
• 作为产物：
  描述：

  Me3SnCH2CH(P(O)(OPr-i)2)2 在 etherial HCl 作用下， 以 乙醚 为溶剂， 以90%的产率得到Me2SnClCH2CH(P(O)(OPr-i)2)2
  参考文献：
  名称：

  Weichmann, Horst; Richter, Frank, Zeitschrift fur Chemie, 1989, vol. 29, p. 409 - 410

  摘要：

  DOI：

文献信息

• The structural behaviour of 2,2-functionally disubstituted triorganotin chlorides
  作者：F Richter、M Dargatz、H Hartung、D Schollmeyer、H Weichmann

  DOI：10.1016/0022-328x(95)06047-z

  日期：1996.5

  A series of 13 2,2-difunctional triorganotin chlorides of the general formula Me(2)(Cl)SnCH2CH(X=O)Y=O(X=O, Y=O=P(O)R(2), C(O)R; R=(OPr)-Pr-i, Oet, Ph) has been synthesized by chlorination of the corresponding tetraorganotin compounds Me(3)SnCH(2)CH(X=O)Y=O with HCl in diethyl ether. The crystal structure determination of Me(2)(Cl)SnCH2[P(O)((OPr)-Pr-i)(2)](2) (VIII), IR spectroscopic data and NMR studies reveal, for the title compounds, molecular structures in which the tin atom, approaches a trigonal-bipyramidal pentacoordinated ligand arrangement as result of an intramolecular Sn ... O interaction of one of the two functional groups X=O or Y=O respectively, In solution the compounds undergo a ligand exchange process which has been investigated by NMR. A mechanism of this process is suggested.
• Weichmann, Horst; Richter, Frank, Zeitschrift fur Chemie, 1989, vol. 29, p. 409 - 410
  作者：Weichmann, Horst、Richter, Frank

  DOI：——

  日期：——
• 2,2-Functionally disubstituted organotin compounds: synthesis and reactivity
  作者：F. Richter、H. Weichmann

  DOI：10.1016/0022-328x(94)88031-x

  日期：1994.2

  A series of 2,2-difunctional organotin compounds of the general type Me(3)SnCH(2)CHXY (X, Y = P(O)R(2) or C(O)R; R = (OPr)-Pr-i, OEt or Ph) has been synthesized by stannylmethylation of the appropriate 2,2-difunctional methanides Na[CHXY] with iodomethyl trimethylstannane. Derivatives with phenyl groups on tin cannot be made by this method. The reactions of the title compounds at the tin atom and at the acidic CH group of the bridging carbon atom and modifications of the functional P(O)R(2) and C(O)R groups are described.