5-methylsalicylaldehydepropanesulfonylhydrazone | 1043885-75-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-methylsalicylaldehydepropanesulfonylhydrazone
• CAS: 1043885-75-1
• 化学式: C₁₁H₁₆N₂O₃S
• 分子量: 256.326
• InChiKey: CYZBZNCNNOCWGB-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  5-methylsalicylaldehydepropanesulfonylhydrazone 、 nickel dichloride 在 sodium hydroxide 作用下， 以 甲醇 、 乙腈 为溶剂， 以45%的产率得到Ni(5-methylsalicylaldehydepropanesulfonylhydrazone)2
  参考文献：
  名称：

  Synthesis, characterization and antibacterial activity of new sulfonyl hydrazone derivatives and their nickel(II) complexes

  摘要：

  Prophane sulfonic acid hydrazide (psh: CH3CH2CH2SO2NHNH2) derivatives as salicylaldehydeprophanesulfonylhydrazone (salpsh), 5-methylsalicylaldehydeprophanesulfonylhydrazone (5-msalpsh), 2-hydroxyacetophenoneprophanesulfonylhydrazone (afpsh), 5-methyl-2-hydroxyacetophenoneprophanesulfonylhydrazone (5-mafpsh) and their Ni(II) complexes have been synthesized. The structure of these compounds has been investigated by using elemental analysis, FFIR, H-1 NMR, LC/MS, UV-vis spectrophotometric method, magnetic susceptibility and conductivity measurements. The complexes were found to have general compositions [NiL2]. Square-planer structures are proposed for the Ni(II) complexes on the basis of magnetic evidence, electronic spectra and TGA data. Bacterial activities of sulfonyl hydrazone compounds were studied against gram-positive bacteria: Staphylococcus aureus, Bacillus subtilis, Bacillus magaterium and gram-negative bacteria: Salmonella enteritidis, Escherichia coli by using minimum inhibitory concentrations (MICs) method. (C) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2007.08.012