N-Ethyl-N-piperidylmethylanilin | 29608-04-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-Ethyl-N-piperidylmethylanilin
• 英文别名: N-ethyl-N-(piperidin-1-ylmethyl)aniline
• CAS: 29608-04-6
• 化学式: C₁₄H₂₂N₂
• 分子量: 218.342
• InChiKey: GDPXOKMSFQHPBW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• METHOD OF PREVENTING OR TREATING VIRAL INFECTION
  申请人：Department of Health and Human Services The United States of America, as Represented by the Secretary,

  公开号：US20130123344A1

  公开（公告）日：2013-05-16

  Disclosed are compounds and pharmaceutical compositions containing compounds that inhibit JMJD2 proteins, including those of the formula (I): wherein R 1 , R 2 , R 3 , R 4 , and R 5 are as defined herein or pharmaceutically acceptable salts thereof. Also disclosed is a method of preventing or treating a viral infection of a host, comprising administering to the host an effective amount of an inhibitor of the JMJD2 family of histone demethylases, for example, a compound of the formula (I). The viral infection may be a primary infection, reactivation of a virus after latency in a host, or may be in a mammal that has undergone, is undergoing, or will undergo immunosuppressive therapy.
• US8871789B2
  申请人：——

  公开号：US8871789B2

  公开（公告）日：2014-10-28