N.N'-Bis-<2.4.6-trimethyl-benzyliden>-meso-1.2-diphenyl-aethylendiamin | 444651-67-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: N.N'-Bis-<2.4.6-trimethyl-benzyliden>-meso-1.2-diphenyl-aethylendiamin
• 英文别名: N-[(1S,2R)-1,2-diphenyl-2-[(2,4,6-trimethylphenyl)methylideneamino]ethyl]-1-(2,4,6-trimethylphenyl)methanimine
• CAS: 444651-67-6
• 化学式: C₃₄H₃₆N₂
• 分子量: 472.673
• InChiKey: LVDZSYMRHIOFDF-AQOUDTPCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.3
• 重原子数：
  36
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  24.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苯甲醛 、 alkaline earth salt of/the/ methylsulfuric acid 以 甲苯 为溶剂， 生成 N.N'-Bis-<2.4.6-trimethyl-benzyliden>-meso-1.2-diphenyl-aethylendiamin
  参考文献：
  名称：

  Staab,H.A.; Voegtle,F., Chemische Berichte, 1965, vol. 98, p. 2681 - 2690

  摘要：

  DOI：

文献信息

• Discovery of chiral catalysts by asymmetric activation for highly enantioselective diethylzinc addition to imines: using racemic and achiral diimines as effective activators
  作者：Hua Liu、Hai-Le Zhang、Shuang-Jun Wang、Ai-Qiao Mi、Yao-Zhong Jiang、Liu-Zhu Gong

  DOI：10.1016/j.tetasy.2005.07.014

  日期：2005.9

  A library of chiral zinc complexes formed in Situ by the combination of achiral and racemic diimines with 3,3'-di(3,5-ditrifluoromethylphenyl)-BINOL and diethylzinc were evaluated in the asymmetric addition of diethylzine to N-acylimines. In the presence of 10 mol % of chiral ligand 4 and racemic diimine 5, high enantioselectivities of up to 97% ee and yields of up to 96% were achieved for a wide range of aromatic imines in dichloromethane at -30 degrees C. (c) 2005 Elsevier Ltd. All rights reserved.