Salvianolic acid G | 136112-79-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噁庚英
• 英文名称: Salvianolic acid G
• 英文别名: 4,5,17-trihydroxy-11-oxo-2-oxatetracyclo[8.7.1.03,8.014,18]octadeca-1(17),3(8),4,6,9,14(18),15-heptaene-12-carboxylic acid
• CAS: 136112-79-3
• 化学式: C₁₈H₁₂O₇
• 分子量: 340.3
• InChiKey: AMPDZVASNOBSQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  25
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  124
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• TRADITIONAL CHINESE MEDICINE PREPARATION FOR CARDIO-CEREBRAL BLOOD VESSEL DISEASES AND ITS PREPARING METHOD
  申请人：Tianjin Tasly Pharmaceutical Co., Ltd.

  公开号：EP1741439A1

  公开（公告）日：2007-01-10

  The present invention discloses a traditional Chinese medicine preparation for cardio-cerebral blood vessel diseases, it is prepared through extracting danshen and Notoginseng by lye, precipitating with alcohol, concentrating, and adding other medicine and excipients. Then using the HAPLY-MS and HAPLY fingerprint Atlas to characterize its Physicochemical properties completely. Using the fingerprint Atlas analysis method of the present invention, the structure and comparative content of biologically active component can be known. Characterization of the physical chemical properties of danshen and Notoginseng of traditional Chinese medicine preparation with this way is better than other methods of the prior art.

  本发明公开了一种治疗心脑血管疾病的中药制剂，它是通过碱液提取丹参和田七，用乙醇沉淀，浓缩，加入其他药物和辅料制备而成。然后利用 HAPLY-MS 和 HAPLY 指纹图谱对其理化性质进行全面表征。利用本发明的指纹图谱分析方法，可以知道生物活性成分的结构和比较含量。用这种方法表征中药制剂丹参和田七的理化性质优于现有技术的其他方法。
• Traditional chinese medicine preparation for cardio-cerebral blood vessel diseases and its preparing method
  申请人：Cheng Yiyu

  公开号：US20070071834A1

  公开（公告）日：2007-03-29

  The present invention discloses a traditional Chinese medicine preparation for cardio-cerebral blood vessel diseases, it is prepared through extracting danshen and Notoginseng by lye, precipitating with alcohol, concentrating, and adding other medicine and excipients. Then using the HAPLY-MS and HAPLY fingerprint Atlas to characterize its Physicochemical properties completely. Using the fingerprint Atlas analysis method of the present invention, the structure and comparative content of biologically active component can be known. Characterization of the physical chemical properties of danshen and Notoginseng of traditional Chinese medicine preparation with this way is better than other methods of the prior art.
• US7396545B2
  申请人：——

  公开号：US7396545B2

  公开（公告）日：2008-07-08