Stigmastanediol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: Stigmastanediol
• 英文别名: 17-(5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5-diol
• 化学式: C₂₉H₅₂O₂
• 分子量: 432.7
• InChiKey: MJZYBROJFJAPOE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Hot melt adhesive composition
  申请人：Yasuda Kyouyu

  公开号：US20070135543A1

  公开（公告）日：2007-06-14

  [Problem] To provide an adhesive composition which is used for fixing a semiconductor wafer or the like onto a substrate, exhibits firm adhesion with high heat resistance in the wafer grinding stage and is melted by heating to enable easy peeling after the completion of the wafer grinding stage. [Means to solve problem] The hot-melt adhesive composition of the invention is a composition containing as a main component a crystalline compound having a melting temperature of 50 to 300° C., and has a melting temperature width of not more than 30° C. and a melt viscosity of not more than 0.1 Pa·s. The crystalline compound as a main component is desired to be an organic compound composed of elements of C, H and O only and having a molecular weight of not more than 1000, preferably an aliphatic compound or an alicyclic compound, particularly preferably a compound having a steroid skeleton and/or a hydroxyl group.
• PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LIVER CANCER COMPRISING STIGMASTEROL AND 5 BETA-HYDROXYSITOSTANOL ISOLATED FROM NAVICULA INCERTA
  申请人：PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY CO

  公开号：US20140057884A1

  公开（公告）日：2014-02-27

  A novel use of phytosterol isolated from Navicula incerta having effect of preventing or treating liver cancer is provided. Accordingly, a composition for preventing or treating liver cancer including stigmasterol and 5β-hydroxysitostanol isolated from Navicula incerta as an active ingredient is provided. Accordingly, and 5β-hydroxysitostano upregulate expression of genes involved with hepatoma cell apoptosis inducing factors, while downregulating genes involved with hepatoma cell apoptosis inhibiting genes, thereby lead into effective prevention or treatment of liver cancer.