3-(2,4-dihydroxyphenyl)-2-[(4-hydroxy-3-methoxyphenyl)methyl]-2H-furan-5-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 3-(2,4-dihydroxyphenyl)-2-[(4-hydroxy-3-methoxyphenyl)methyl]-2H-furan-5-one
• 化学式: C₁₈H₁₆O₆
• 分子量: 328.3
• InChiKey: AEJPJQHQRQSQJZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  96.2
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• [EN] NOVEL COMPOUNDS AS MEMORY ENHANCERS<br/>[FR] NOUVEAUX COMPOSÉS À TITRE DE STIMULATEURS DE MÉMOIRE
  申请人：PANJAB UNIVERSITY

  公开号：WO2013179309A1

  公开（公告）日：2013-12-05

  The present invention relates to a new series of chemical compounds with a novel norneolignan skeleton (chemical formula I) possessing a biological activity on the central nervous system (CNS), especially memory-enhancing and acetylcholinesterase inhibitory activity, individually, or in combination thereof. The novel compounds of a new series have been named as Clitorienolactones. (The chemical formula should be inserted here.) wherein R1, R2 is H, OH or OCH3; Ring A and B may be mono- to polysubstituted