2,3-Dihydro-7-hydroxymethyl-2-(1-hydroxy-1-methylethyl)-4-methoxy-5h-furo-[3,2-g]-[1]-benzopyran-5-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2,3-Dihydro-7-hydroxymethyl-2-(1-hydroxy-1-methylethyl)-4-methoxy-5h-furo-[3,2-g]-[1]-benzopyran-5-one
• 英文别名: 7-(hydroxymethyl)-2-(2-hydroxypropan-2-yl)-4-methoxy-2,3-dihydrofuro[3,2-g]chromen-5-one
• 化学式: C₁₆H₁₈O₆
• 分子量: 306.31
• InChiKey: ATDBDSBKYKMRGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,3-Dihydro-7-hydroxymethyl-2-(1-hydroxy-1-methylethyl)-4-methoxy-5h-furo-[3,2-g]-[1]-benzopyran-5-one 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 36.0h， 生成
  参考文献：
  名称：

  一种升麻素衍生物及其制备方法与药用用途

  摘要：

  本发明属于合成医药小分子技术领域，本发明提供了一种升麻素衍生物及其制备方法与药用用途。本发明以升麻素为起始原料，在不使用强氧化剂和剧毒溶剂的情况下，以温和的反应条件制备出了具有显著的药理活性的升麻素衍生物，且目标产物的收率较高，为防风药材的质量开发与应用提供了理论依据。

  公开号：

  CN117865976A

文献信息

• Compositions containing enriched natural crocin and/or crocetin, and their therapeutic or nutraceutical uses
  申请人：Gao Song

  公开号：US10842805B2

  公开（公告）日：2020-11-24

  The invention relates to unique compositions containing enriched and purified natural crocin and/or crocetin for prevention and/or treatment of cancers and other conditions and diseases. Compositions comprise mainly enriched or purified natural crocin or crocetin or combination of both and possible other active phytochemicals. A composition is used as functional food, drink, dietary supplement, or therapeutic dosage to a human orally or through other appropriate way (parenteral, percutaneous, rectal, mucosal, intranasal or topical administration). A method of natural crocin and crocetin enriching and purification is revealed.

  本发明涉及含有富集和纯化的天然羊角霉素和/或羊胎素的独特组合物，用于预防和/或治疗癌症及其他病症和疾病。组合物主要包括富集或纯化的天然巴豆素或巴豆黄素或二者的组合以及可能的其他活性植物化学物质。组合物可作为功能性食品、饮料、膳食补充剂或治疗剂量，口服或通过其他适当方式（肠外、经皮、直肠、粘膜、鼻内或局部给药）给人服用。揭示了一种富集和提纯天然巴豆素和藏红花素的方法。
• Compositions Containing Enriched Natural Crocin and/or Crocetin, and Their Therapeutic or Nutraceutical Uses
  申请人：Gao Song

  公开号：US20140141082A1

  公开（公告）日：2014-05-22

  The invention relates to unique compositions containing enriched and purified natural crocin and/or crocetin for prevention and/or treatment of cancers and other conditions and diseases. Compositions comprise mainly enriched or purified natural crocin or crocetin or combination of both and possible other active phytochemicals. A composition is used as functional food, drink, dietary supplement, or therapeutic dosage to a human orally or through other appropriate way (parenteral, percutaneous, rectal, mucosal, intranasal or topical administration). A method of natural crocin and crocetin enriching and purification is revealed.
• ENDURANCE FORMULATION AND USE
  申请人：GLANBIA NUTRITIONALS (IRELAND) LIMITED

  公开号：US20160213673A1

  公开（公告）日：2016-07-28

  The present disclosure provides compositions and formulations containing dihydrocapsiate, caffeine and arginine as well as methods of making and using the compositions and formulations. The compositions and formulations of the present disclosure increase human endurance during times of physical activity.
• METHODS FOR AUTHENTICATING BOTANICALS USING A MARKER COMPOUND'S RELATED CHROMATOGRAPHIC PROFILE AND MASS SPECTRAL PROFILE JOINTLY
  申请人：Waters Technologies Corporation

  公开号：US20190339238A1

  公开（公告）日：2019-11-07

  A method is provided for authenticating a botanical. The method includes identifying at least one marker compound of the botanical. A sample comprising the botanical is injected into a chromatography system that includes a mobile phase delivery module, an autosampler, a chromatography column, a chromatography column manager, and at least one detector. The method also includes extracting a chromatogram of the at least one marker compound and extracting a spectrum at a chromatographic peak retention time of the at least one marker compound. The method also includes quantifying at least one peak of the extracted chromatogram and quantifying at least one band of the extracted spectrum. The quantified at least one peak of the extracted chromatogram and the quantified at least one band of the extracted spectrum are compared to a set of authentication criteria to determine authenticity of the botanical.
• METHODS FOR ENHANCING EYEBROW APPEARANCE
  申请人：RMV TRADEMARKS, LLC

  公开号：US20200146972A1

  公开（公告）日：2020-05-14

  Compositions comprising from about 0.5 to about 40 percent by weight of an extract of black cohosh, from about 0.5 to about 20 percent by weight of nonionic surfactant, and from about to 40 about 99 percent by weight of hydroxylated solvent are effective in enhancing eyebrow appearance.