Taraxacin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 英文名称: Taraxacin
• 英文别名: 1,5,8-trimethyl-3a,4-dihydroazuleno[6,5-b]furan-2,6-dione
• 化学式: C₁₅H₁₄O₃
• 分子量: 242.27
• InChiKey: BAHMQESJBKGPTE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• COMPOSITION FOR PROTECTING LIVER COMPRISING DANDELION EXTRACT AND LEMON BALM EXTRACT
  申请人：Phytonutrimedi Co., Ltd.

  公开号：EP3653220A2

  公开（公告）日：2020-05-20

  The present invention can effectively protect a liver from oxidative stress caused by liver damage by significantly reducing the aspartate aminotransferase (AST) and alanine aminotransferase (ALT) values, which are widely known as indicators of liver damage when applied to liver toxicity animal models. The present invention relates to a composition for protecting a liver comprising a dandelion extract and a lemon balm extract as active ingredients that can be usefully used for preventing, ameliorating or treating liver damage, wherein the composition is characterized by comprising a dandelion extract and a lemon balm extract as active ingredients.

  本发明可显著降低天冬氨酸氨基转移酶（AST）和丙氨酸氨基转移酶（ALT）值，从而有效保护肝脏免受肝损伤引起的氧化应激，而天冬氨酸氨基转移酶（AST）和丙氨酸氨基转移酶（ALT）值在应用于肝毒性动物模型时被广泛认为是肝损伤的指标。本发明涉及一种保护肝脏的组合物，该组合物包含蒲公英提取物和柠檬香膏提取物作为活性成分，可有效用于预防、改善或治疗肝损伤，其中该组合物的特征在于包含蒲公英提取物和柠檬香膏提取物作为活性成分。
• Medicament containing taraxacum plant root extract for treatment or prevention of cancer, and method for preparing same
  申请人：Pandey Siyaram

  公开号：US10179156B2

  公开（公告）日：2019-01-15

  The present invention relates to an improved method for preparing a medicament comprising a Taraxacum plant root extract for the treatment or prevention of a cancer. In one aspect, the method comprises freezing Taraxacum plant root to obtain a frozen root stock, said freezing step being selected to effect at least partial disruption of one or more root cells; dry grinding the frozen root stock to obtain a ground root powder, wherein during said dry grinding step the frozen root stock is maintained at a grinding temperature below about 40° C.; steeping the ground root powder with a solvent to obtain a suspension having a liquid extract portion and a solid particle portion; and separating the liquid extract portion from the solid particle portion to provide a separated liquid extract for use in the medicament.

  本发明涉及一种改进的方法，用于制备包含蒲公英植物根提取物的药物，以治疗或预防癌症。在一个方面中，该方法包括冷冻蒲公英植物根以获得冷冻根浆，所述冷冻步骤被选择用于至少部分破坏一个或多个根细胞；干磨冷冻根浆以获得研磨根粉，其中在所述干磨步骤中，冷冻根浆保持在低于约 40°C 的研磨温度下；用溶剂浸泡研磨根粉以获得具有液体提取物部分和固体颗粒部分的悬浮液；以及从固体颗粒部分分离液体提取物部分以提供用于药剂的分离液体提取物。
• MEDICAMENT CONTAINING TARAXACUM PLANT ROOT EXTRACT FOR TREATMENT OR PREVENTION OF CANCER, AND METHOD FOR PREPARING SAME
  申请人：University of Windsor

  公开号：EP2817017A1

  公开（公告）日：2014-12-31
• Homeopathic Remedies and Methods for Enhancing Weight Loss
  申请人：McCann Sarah

  公开号：US20140037753A1

  公开（公告）日：2014-02-06

  Homeopathic compositions and formulations are disclosed. In one embodiment, compositions and formulations are disclosed that aid in weight loss and maintenance of a healthy weight. In another embodiment, methods are disclosed for producing homeopathic compositions and formulations. In still another embodiment, methods are disclosed for helping an individual lose weight.
• Medicament Containing Taraxacum Plant Root Extract for Treatment or Prevention of Cancer, and Method for Preparing Same
  申请人：Pandey Siyaram

  公开号：US20150010665A1

  公开（公告）日：2015-01-08

  The present invention relates to an improved method for preparing a medicament comprising a Taraxacum plant root extract for the treatment or prevention of a cancer. In one aspect, the method comprises freezing Taraxacum plant root to obtain a frozen root stock, said freezing step being selected to effect at least partial disruption of one or more root cells; dry grinding the frozen root stock to obtain a ground root powder, wherein during said dry grinding step the frozen root stock is maintained at a grinding temperature below about 40° C.; steeping the ground root powder with a solvent to obtain a suspension having a liquid extract portion and a solid particle portion; and separating the liquid extract portion from the solid particle portion to provide a separated liquid extract for use in the medicament.