2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]ethanesulfonic acid | 1808218-24-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 2-[4-(3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoylamino]ethanesulfonic acid
• CAS: 1808218-24-7
• 化学式: C₂₆H₄₅NO₆S
• 分子量: 499.7
• InChiKey: BHTRKEVKTKCXOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  34
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  132
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Methods of treating SARS-COV-2 infections
  申请人：Tyme, Inc.

  公开号：US10905698B1

  公开（公告）日：2021-02-02

  The disclosure is directed to methods of using TUDCA, or a pharmaceutically acceptable salt thereof, or a derivative thereof, for the treatment of SARS-CoV-2 infections.

  本公开涉及使用 TUDCA 或其药学上可接受的盐或其衍生物治疗 SARS-CoV-2 感染的方法。
• COMPOUND, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, RESIST FILM USING SAME, RESIST-COATED MASK BLANK, PHOTOMASK, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20160116840A1

  公开（公告）日：2016-04-28

  Provided is an active light sensitive or radiation sensitive resin composition which contains a compound (A) represented by General Formula (I) or (II): in the formulae, each of Y 1 and Y 2 represents a monovalent organic group; each of M 1 + and M 2 + represents an organic onium ion; each of X 1 and X 2 represents a group that is represented by —S—, —NH—, or —NR 1 —; R 1 represents a monovalent organic group; each of n1 and n2 represents an integer of 1 or more; and R 1 and Y 1 or Y 2 may bond with each other to form a ring.
• METHODS OF TREATING SARS-COV-2 INFECTIONS
  申请人：Tyme, Inc.

  公开号：US20210353645A1

  公开（公告）日：2021-11-18

  The disclosure is directed to methods of using TUDCA, or a pharmaceutically acceptable salt thereof, or a derivative thereof, for the treatment of SARS-CoV-2 infections.
• US9904167B2
  申请人：——

  公开号：US9904167B2

  公开（公告）日：2018-02-27
• [EN] METHODS OF USING BILE ACIDS TO TREAT VIRAL INFECTIONS<br/>[FR] MÉTHODES D'UTILISATION D'ACIDES BILIAIRES POUR TRAITER DES INFECTIONS VIRALES
  申请人：HOFFMAN STEVEN

  公开号：WO2021231934A1

  公开（公告）日：2021-11-18

  The disclosure is directed to methods of using hydrophilic bile acids for the treatment of viral infections.