5-methyl-10H-phenazine-1-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 5-methyl-10H-phenazine-1-carboxylic acid
• 化学式: C₁₄H₁₂N₂O₂
• 分子量: 240.26
• InChiKey: BMZNIKPIYJQVSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  52.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Diagnostic system and process for rapid bacterial infection diagnosis
  申请人：Northeastern University

  公开号：US10316348B2

  公开（公告）日：2019-06-11

  Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of Pseudomonas aeruginosa. In some embodiments, an inexpensive, disposable electrochemical sensor can be used to rapidly screen for the presence of P. aeruginosa in clinical wound effluent samples.

  本发明提供了通过检测焦花青素来监测由铜绿假单胞菌组成的生物膜的活力的方法和装置。本发明涉及电化学方法和装置，这些方法和装置提供了一种简单、廉价的替代方法，可立即识别由于铜绿假单胞菌的存在而导致的细菌感染。在某些实施方案中，一种廉价的一次性电化学传感器可用于快速筛查临床伤口流出物样本中是否存在铜绿假单胞菌。
• DIAGNOSTIC SYSTEM AND PROCESS FOR RAPID BACTERIAL INFECTION DIAGNOSIS
  申请人：Northeastern University

  公开号：EP3194373A2

  公开（公告）日：2017-07-26
• METHOD FOR MONITORING VIABILITY OF A BIOFILM OF PSEUDOMONAS AERUGINOSA BASED ON THE ELECTROCHEMICAL DETECTION OF PYOCYANIN
  申请人：Northeastern University

  公开号：EP3194373B1

  公开（公告）日：2021-03-31
• Diagnostic System and Process for Rapid Bacterial Infection Diagnosis
  申请人：Northeastern University

  公开号：US20170247739A1

  公开（公告）日：2017-08-31

  Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of Pseudomonas aeruginosa. In some embodiments, an inexpensive, disposable electrochemical sensor can be used to rapidly screen for the presence of P. aeruginosa in clinical wound effluent samples.
• [EN] DIAGNOSTIC SYSTEM AND PROCESS FOR RAPID BACTERIAL INFECTION DIAGNOSIS<br/>[FR] SYSTÈME DIAGNOSTIQUE ET PROCÉDÉ DE DIAGNOSTIC RAPIDE D'UNE INFECTION BACTÉRIENNE
  申请人：UNIV NORTHEASTERN

  公开号：WO2016044417A2

  公开（公告）日：2016-03-24

  Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas aeruginosa bacteria are provided by detecting pyocyanin.