5,7-Dihydroxy-10-methoxy-2-methyl-2-(4-methylpent-3-enyl)pyrano[3,2-b]xanthen-6-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 5,7-Dihydroxy-10-methoxy-2-methyl-2-(4-methylpent-3-enyl)pyrano[3,2-b]xanthen-6-one
• 英文别名: 5,7-dihydroxy-10-methoxy-2-methyl-2-(4-methylpent-3-enyl)pyrano[3,2-b]xanthen-6-one
• 化学式: C₂₄H₂₄O₆
• 分子量: 408.451
• InChiKey: BSPFIFWAAPLSFN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  smeathxanthone B 、 碘甲烷 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 生成 5,7-Dihydroxy-10-methoxy-2-methyl-2-(4-methylpent-3-enyl)pyrano[3,2-b]xanthen-6-one
  参考文献：
  名称：

  Xanthones from Garcinia smeathmannii (Oliver) and their antimicrobial activity

  摘要：

  Two new xanthones, smeathxanthone A (1) (2-(3,7-dimethyl-2,6-octadienyl)-1,3,5,8-tetrahydroxyxanthone) and smeathxanthone B (2) (5,7,10-trihydroxy-2-methyl-2-(4-methylpent-3-enyl)[2H, 6H]pyrano[3,2-b]xanthen-6-one), have been isolated from the stem bark of Garcinia smeathmannii, and their structures elucidated on the basis of 1D and 2D NMR experiments. 1,3,5-Trihydroxyxanthone and 1,5-dihydroxyxanthone were also obtained. The compounds showed only modest activity against a range of bacteria and yeasts. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.phytochem.2005.03.010

文献信息

• Xanthones from Garcinia smeathmannii (Oliver) and their antimicrobial activity
  作者：Justin Komguem、A.L. Meli、R.N. Manfouo、David Lontsi、F.N. Ngounou、V. Kuete、Hippolyte W. Kamdem、Pierre Tane、Bonaventure T. Ngadjui、Beiban L. Sondengam

  DOI：10.1016/j.phytochem.2005.03.010

  日期：2005.7

  Two new xanthones, smeathxanthone A (1) (2-(3,7-dimethyl-2,6-octadienyl)-1,3,5,8-tetrahydroxyxanthone) and smeathxanthone B (2) (5,7,10-trihydroxy-2-methyl-2-(4-methylpent-3-enyl)[2H, 6H]pyrano[3,2-b]xanthen-6-one), have been isolated from the stem bark of Garcinia smeathmannii, and their structures elucidated on the basis of 1D and 2D NMR experiments. 1,3,5-Trihydroxyxanthone and 1,5-dihydroxyxanthone were also obtained. The compounds showed only modest activity against a range of bacteria and yeasts. (c) 2005 Elsevier Ltd. All rights reserved.