N6-Methylagmatine | 77414-15-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N6-Methylagmatine
• 英文别名: 1-(4-aminobutyl)-2-methylguanidine
• CAS: 77414-15-4
• 化学式: C₆H₁₆N₄
• 分子量: 144.22
• InChiKey: CEZLGLLDSAKBNX-UHFFFAOYSA-N

物化性质

• 沸点：
  220.1±42.0 °C(Predicted)
• 密度：
  1.10±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  76.4
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• Amino acid compositions
  申请人：ThermoLife International, LLC

  公开号：US10435356B1

  公开（公告）日：2019-10-08

  A composition is disclosed that includes a Nitrate or a Nitrite of an Amino Acid Compound selected from the group consisting of Arginine, Agmatine, Beta Alanine, Citrulline, Creatine, Glutamine, L-Histidine, Isoleucine, Leucine, Norvaline, Ornithine, Valine, Aspartic Acid, Cysteine, Glycine, Lysine, Methionine, Proline, Tyrosine, and Phenylalanine, wherein the composition is formulated to deliver an effective amount of the Nitrate or Nitrite of the Amino Acid Compound to prevent the development of nitrate tolerances, to increase bioabsorption of amino acids, to increase the vasodilative characteristics of amino acids, or to increase athletic performance in a human or animal. The composition may be in a dosage form selected from the group consisting of a capsule, a cachet, a pill, a tablet, a powder, a granule, a pellet, a bead, a particle, a troche, a lozenge, a gel, a liquid, a suspension, a solution, an elixir, and a syrup.

  本发明公开了一种组合物，其中包括选自精氨酸、阿甘氨酸、β-丙氨酸、瓜氨酸、肌酸、谷氨酰胺、L-组氨酸、异亮氨酸、亮氨酸、正缬氨酸、鸟氨酸、缬氨酸、天冬氨酸、半胱氨酸、甘氨酸、赖氨酸、蛋氨酸、脯氨酸、酪氨酸和苯丙氨酸的氨基酸化合物的硝酸盐或亚硝酸盐、其中，组合物的配制是为了提供有效量的氨基酸化合物硝酸盐或亚硝酸盐，以防止硝酸盐耐受性的发展，增加氨基酸的生物吸收，增加氨基酸的血管扩张特性，或增加人或动物的运动表现。组合物的剂型可选自胶囊、胶囊剂、丸剂、片剂、粉剂、颗粒剂、球剂、珠剂、微粒剂、锭剂、凝胶剂、液体剂、悬浮剂、溶液剂、酏剂和糖浆剂。
• Method of safely administering nitrate dietary supplements and compositions
  申请人：ThermoLife International, LLC

  公开号：US10646508B1

  公开（公告）日：2020-05-12

  A method of making a composition or a dietary supplement is provided, the method comprising combining a quantity of a Nitrate with a quantity of an Amino Acid Compound, wherein the combining of the Nitrate with the Amino Acid Compound reduces a side effect or toxicity of the Nitrate. Also provided is a method of safely administering to a subject a Nitrate with a reduced side effect or toxicity, the method comprising: combining a quantity of the Nitrate with a quantity of an Amino Acid Compound in a composition or a dietary supplement, wherein the combining of the Nitrate with the Amino Acid Compound reduces the side effect or toxicity of the Nitrate; and safely administering to the subject the composition or dietary supplement comprising the Nitrate with the reduced side effect or toxicity.

  提供了一种制造组合物或膳食补充剂的方法，该方法包括将一定量的硝酸盐与一定量的氨基酸化合物结合，其中硝酸盐与氨基酸化合物的结合降低了硝酸盐的副作用或毒性。还提供了一种向受试者安全施用副作用或毒性降低的硝酸盐的方法，该方法包括：在组合物或膳食补充剂中将一定量的硝酸盐与一定量的氨基酸化合物结合，其中硝酸盐与氨基酸化合物的结合降低了硝酸盐的副作用或毒性；以及向受试者安全施用包含副作用或毒性降低的硝酸盐的组合物或膳食补充剂。