Cholesterylbutyrat

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: Cholesterylbutyrat
• 英文别名: cholesteryl butyrate；Cholestenyl butyrate；[10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] butanoate
• 化学式: C₃₁H₅₂O₂
• mdl: MFCD00321179
• 分子量: 456.753
• InChiKey: CKDZWMVGDHGMFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.9
• 重原子数：
  33
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS
  申请人：Ugisense AG

  公开号：US20170166900A1

  公开（公告）日：2017-06-15

  The invention relates to new peptide nucleic acid monomers and peptide nucleic acid oligomers comprising a dialkylamine side chain substituted with phosphonic acid ester group(s) or phosphonic acid group(s), and to the uses thereof.

  本发明涉及新的肽核酸单体和肽核酸寡聚物，包括具有磷酸酯基团或磷酸基团取代的二烷基胺侧链，以及其用途。
• CELLULOSE ACYLATE FILM, RETARDER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICES
  申请人：HAGIO Hiroyuki

  公开号：US20110236603A1

  公开（公告）日：2011-09-29

  A cellulose acylate film comprising at least one cellulose acylate, at least one sterol derivative represented by formula (1), and at least one saccharide derivative and/or at least one oligomer plasticizer is disclosed. R 1 , R 2 and R 3 represents a hydrogen atom, a hydroxyl group or a substituent represented by -L-R*, provided that at least one of them represents the substituent represented by -L-R*; L represents a single bond or a divalent connecting group selected from the group consisting of —O—, —CO—, —CONR 6 —, —CH 2 — and a combination thereof, R* represents a substituted or unsubstituted aromatic ring group, heterocyclic group or alkyl group; R 4 represents a carboxyl group or —CHR 7 —CH(CH 3 ) 2 ; R 5 represents a hydrogen atom or a methyl group.
• ANTIMICROBIAL PEPTIDE DERIVATIVE AND USE THEREOF
  申请人：SI CHUAN UNIVERSITY

  公开号：US20190216939A1

  公开（公告）日：2019-07-18

  The invention relates to the field of biomedicine and particularly to a hydrophobically modified antimicrobial peptide and a use thereof. The technical problem to be solved by the invention is to provide a hydrophobically modified antimicrobial peptide, the hydrophobic modification is to couple a hydrophobic fragment at the nitrogen terminal of the antimicrobial peptide. The invention further provides a micelle prepared from the hydrophobically modified antimicrobial peptide, and use of the hydrophobically modified antimicrobial peptide and the micelle in preparing antimicrobial drugs, nucleic acid transporter, immune adjuvant and the like. Due to small molecular weight, the antimicrobial peptide of the invention can be conveniently synthesized by Fmoc solid phase polypeptide, and coupled to a hydrophobic fragment by the chemical synthesis method in a simple and feasible way.