α-Thujaplicinol | 16643-33-7

• 分子结构分类: 有机化合物 - 碳氢化合物衍生物 - 环庚三烯酮
• 英文名称: α-Thujaplicinol
• 英文别名: I+/--Thujaplicinol；2,3-dihydroxy-4-propan-2-ylcyclohepta-2,4,6-trien-1-one
• CAS: 16643-33-7
• 化学式: C₁₀H₁₂O₃
• 分子量: 180.203
• InChiKey: DTNGDTFARJMFLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• NEW USES
  申请人：Evocutis plc

  公开号：EP2598208A2

  公开（公告）日：2013-06-05
• Plant Materials Extraction Method
  申请人：Jones David

  公开号：US20070219141A1

  公开（公告）日：2007-09-20

  A process for preparing plant extracts is provided. Plant materials, including tropolones, lignins and polar molecules, are mixed with a liquid polar solvent to form an extraction mixture, which is maintained under extraction conditions effective to extract lignins, polar molecules and at least 50% of the tropolones into the polar solvent to form a pregnant polar solvent liquid phase. The pregnant polar solvent phase is separated from the solid plant materials, and mixed with a substantially immiscible nonpolar solvent under conditions effective to partition the tropolones and lignins substantially into the nonpolar solvent and to partition the polar molecules substantially into the polar solvent to form a partitioned nonpolar solvent phase comprising lignins and tropolones, and a partitioned polar solvent phase comprising the polar molecules, and separating the polar solvent phase from the nonpolar solvent phase to obtain a polar plant extract and a nonpolar plant extract.
• [EN] NEW USES<br/>[FR] NOUVELLES UTILISATIONS
  申请人：SYNTOPIX GROUP PLC

  公开号：WO2012013967A2

  公开（公告）日：2012-02-02

  An antibacterial or anti-acne formulation containing (a) tropone or a substituted tropone and (b) a metal or metal salt selected from copper, copper salts, bismuth, bismuth salts, silver, silver salts, and mixtures thereof, for use in the treatment of either acne or body odour. The substituted tropone may be for example tropolone or hinokitiol.
• [EN] FORMULATIONS CONTAINING TROPOLONOIDS, COPPER SALT AND A SOLVENT SYSTEM<br/>[FR] FORMULATIONS
  申请人：EVOCUTIS PLC

  公开号：WO2012172318A1

  公开（公告）日：2012-12-20

  Topical skin treatment formulation containing a combination of (a) tropone or a substituted tropone and (b) a copper salt, dissolved in a solvent system comprising (i) dimethyl isosorbide; (ii) a C1 to C9 alkyl salicylate; and (iii) a glyceryl fatty acid ester. The solvent system may also comprise an alcohol, a polyoxyalkylene-based solvent, and/or a C1 to C4 alkyl glucose ester. The formulation may be used in the treatment of microbial conditions, in particular acne or body odour. The solvent system assists in the effective dissolution of the tropone and copper salt and in targeting their delivery to relevant sites on the skin.