LIQUID CRYSTAL POLYMERIZED FILMS USING ALIGNMENT FILM AND POLYMERIZABLE LIQUID CRYSTAL COMPOSTION
申请人:JNC CORPORATION
公开号:US20180163135A1
公开(公告)日:2018-06-14
Liquid crystal polymerization films, prepared by applying a polymerizable liquid crystal composition containing a polymerizable liquid crystal compound represented by formula (2) on an alignment film prepared by calcinating a composition containing a polymer represented by a repeating unit of formula (1), and subsequently polymerizing the polymerizable liquid crystal composition.
In formula (1), R
1
is independently a tetravalent group, R
2
is independently a divalent functional group and R
3
is independently a hydrogen atom or a monovalent functional group.
PG
1
-Sp
1
-R
4
-Sp
2
-PG
2
(2)
In formula (2), R
4
represents a divalent group formed by combining five or more and nine or less of alicycles and/or aromatic rings, SP
1
and SP
2
represent a spacer group, and PG
1
and PG
2
represents an alkyl group, an alkoxyl group, a cyano group, fluorine or a polymerizable functional group, in which either group is the polymerizable functional group.
作者:Kwaku Kyei-Baffour、Haroon Mohammad、Mohamed N. Seleem、Mingji Dai
DOI:10.1016/j.bmc.2019.03.034
日期:2019.5
4 µM) and were safe to human keratinocytes. Compound 19, with an additional isonitrile group exhibited improvedactivity against MRSA compared to the first-generation lead compound. This compound emerged as a candidate worthy of further investigation and further reinforced the importance of the isonitrile functionality in the compounds' anti-MRSA activity. In a murine skin wound model, 19 significantly