N-cyclohept-2-en-1-ylidenehydroxylamine | 861575-12-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-cyclohept-2-en-1-ylidenehydroxylamine
• CAS: 861575-12-4
• 化学式: C₇H₁₁NO
• 分子量: 125.17
• InChiKey: ZFCZPTLGARWRFT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  叔丁基亚磺酰氯 、 N-cyclohept-2-en-1-ylidenehydroxylamine 在 三乙胺 作用下， 以 乙醚 为溶剂， 反应 18.0h， 以12%的产率得到
  参考文献：
  名称：

  Convenient Access to Cycloalk-2-enone-Derived N-Sulfonyl Imines

  摘要：

  The first synthesis of N-tosyl imines from various cyclopent-2-enones and cyclohex-2-enones was achieved by direct condensation with tosyl amide in the presence of TiCl(OEt)(3) and Et3N. In addition, N-tert-butylsulfonyl imines from five- to seven-membered cycloalk-2-enones were obtained through formation of the respective oximes and subsequent Hudson reaction. These compounds are easy to handle solids and they are interesting starting materials for a variety of transformations.

  DOI：

  10.1055/s-0034-1378203

文献信息

• Convenient Access to Cycloalk-2-enone-Derived N-Sulfonyl Imines
  作者：Paultheo von Zezschwitz、Sebastian Hirner、Johannes Westmeier、Sandra Gebhardt、Christian Müller

  DOI：10.1055/s-0034-1378203

  日期：——

  The first synthesis of N-tosyl imines from various cyclopent-2-enones and cyclohex-2-enones was achieved by direct condensation with tosyl amide in the presence of TiCl(OEt)(3) and Et3N. In addition, N-tert-butylsulfonyl imines from five- to seven-membered cycloalk-2-enones were obtained through formation of the respective oximes and subsequent Hudson reaction. These compounds are easy to handle solids and they are interesting starting materials for a variety of transformations.