1H-pyrrolo[3,2-d]pyrimidin-7-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯并嘧啶类
• 英文名称: 1H-pyrrolo[3,2-d]pyrimidin-7-ol
• 化学式: C6H5N3O
• InChiKey: JYXWHLZXSOIHAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.62
• 重原子数：
  10.0
• 可旋转键数：
  0.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  61.8
• 氢给体数：
  2.0
• 氢受体数：
  3.0

文献信息

• Fungicidal Azolopyrimidines, Process for Their Preparation and Their Use For Controlling Harmful Fungi, and Also Compositions Comprising Them
  申请人：Dietz Jochen

  公开号：US20100160311A1

  公开（公告）日：2010-06-24

  The present invention relates to azolopyrimidines of the formula I in which the substituents are defined according to the description, to processes and intermediates for preparing these compounds, to compositions comprising them and to their use for controlling phytopathogenic harmful fungi.

  本发明涉及公式I的咪唑嘧啶类化合物，其中取代基根据描述进行定义，涉及制备这些化合物的方法和中间体，包括这些化合物的组合物以及它们用于控制植物病原真菌的用途。
• Use Of 5-Alkyl-6-Phenylalkyl-7-Aminoazolopyrimidines, Novel Azolopyrimidines, Processes For Their Preparation And Compositions Comprising Them
  申请人：Dietz Jochen

  公开号：US20080188494A1

  公开（公告）日：2008-08-07

  The use of 5-alkyl-6-phenylalkyl-7-aminoazolopyrimidines of the formula I in which the variables are as defined below: Y is alkylene, alkenylene or alkynylene, optionally substituted by alkyl groups; R 1 is halogen, cyano, nitro, hydroxyl, mercapto, alkyl, haloalkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxy, haloalkoxy, alkenyloxy, alkynyloxy, alkylthio, NR A R B , alkylcarbonyl, phenyl, naphthyl, or a five- or six-membered saturated, partially unsaturated or aromatic heterocycle which contains one to four heteroatoms from the group consisting of O, N and S; R A , R B is hydrogen, alkyl or alkylcarbonyl; n is zero, 1, 2, 3 or 4; R 2 is alkyl, alkenyl, cycloalkyl, alkoxyalkyl or alkylthioalkyl; R 3 is hydrogen, halogen, cyano, NR A R B , hydroxyl, mercapto, alkyl, haloalkyl, cycloalkyl, alkoxy, alkylthio, cycloalkoxy, cycloalkylthio, carboxyl, formyl, alkylcarbonyl, alkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, phenyl, phenoxy, phenylthio, benzyloxy, benzylthio, alkyl-S(O) m —; m is 0, 1 or 2; A is N or C—R a ; R a is hydrogen or alkyl; where the carbon atoms in Y, R 1 , R 2 , R 3 and R a may be substituted according to the description; for controlling phytopathogenic harmful fungi; novel 5-alkyl-6-phenylalkyl-7-amino-azolopyrimidines, processes for their preparation and compositions comprising them.

  使用以下公式I中的5-烷基-6-苯基烷基-7-氨基咪唑嘧啶，其中变量定义如下：Y为烷基，烯基或炔基，可以通过烷基基团进行取代；R1为卤素，氰基，硝基，羟基，巯基，烷基，卤代烷基，烯基，环烷基，环烯基，烷氧基，卤代烷氧基，烯氧基，炔氧基，烷硫基，NRARB，烷基羰基，苯基，萘基或含有来自O，N和S的一到四个杂原子的五元或六元饱和，部分不饱和或芳香族杂环；RA，RB为氢，烷基或烷基羰基；n为0，1，2，3或4；R2为烷基，烯基，环烷基，烷氧基烷基或烷硫基烷基；R3为氢，卤素，氰基，NRARB，羟基，巯基，烷基，卤代烷基，环烷基，烷氧基，烷硫基，环烷氧基，环烷基硫基，羧基，甲酰基，烷基羰基，烷氧羰基，烯氧羰基，炔氧羰基，苯基，苯氧基，苯基硫基，苄氧基，苄基硫基，烷基-S（O）m-；m为0，1或2；A为N或C-Ra；Ra为氢或烷基；其中Y，R1，R2，R3和Ra中的碳原子可以根据描述进行取代；用于控制植物病原真菌的新型5-烷基-6-苯基烷基-7-氨基咪唑嘧啶，其制备方法和包含它们的组合物。
• 5,6-Dialkyl-7-Aminoazolopyrimidines, Their Preparation and Their Use For Controlling Harmful Fungi, and Compositions Comprising These Compounds
  申请人：Schäfer Peter

  公开号：US20080188493A1

  公开（公告）日：2008-08-07

  5,6-Dialkyl-7-aminoazolopyrimidines of the formula I in which the substituents are as defined below: R 1 is haloalkyl, haloalkoxyalkyl, alkoxyhaloalkyl, alkenyl, haloalkenyl, alkynyl oder haloalkynyl; R 2 is alkyl, alkoxyalkyl, alkenyl or alkynyl; where R 1 and/or R 2 may be substituted according to the description; A is N or CH, and R 3 is CH 3 and, if A is CH, additionally hydrogen; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

  公式I中的5,6-二烷基-7-氨基咯嗪嘧啶，其中取代基如下定义：R1为卤代烷基、卤代烷氧基烷基、烷氧卤代烷基、烯基、卤代烯基、炔基或卤代炔基；R2为烷基、烷氧基烷基、烯基或炔基；其中R1和/或R2可根据描述被取代；A为N或CH，R3为CH3，如果A为CH，则还有氢；制备这些化合物的过程和中间体，包含它们的组合物和它们用于控制植物病原真菌的用途。
• 5,6-Dialkyl-7-Aminoazolopyrimidines, Their Preparation and Their Use for Controlling Harmful Fungi, and Compositions Comprising These Compounds
  申请人：Schafer Peter

  公开号：US20080207455A1

  公开（公告）日：2008-08-28

  5,6-Dialkyl-7-aminoazolopyrimidines of the formula I in which the substituents are as defined below: R 1 is alkyl or alkoxyalkyl, where the aliphatic groups may be substituted as defined in the description; R 2 is CHR x CH 3 , cyclopropyl, CH═CH 2 or CH 2 CH═CH 2 ; R x is hydrogen, CH 3 or CH 2 CH 3 or halomethyl; A is N or CH; R 3 is methyl, and, if A is CH, additionally hydrogen; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi. 5,6-Dialkyl-7aminoazolopyrimidines, their preparation and their use for controlling harmful fungi, and compositions comprising these compounds

  式I中的5,6-二烷基-7-氨基咪唑嘧啶，其中取代基定义如下： R1为烷基或烷氧基烷基，其中脂肪族基可按照描述中定义进行取代； R2为CHRxCH3，环丙基，CH═CH2或CH2CH═CH2； Rx为氢，CH3或CH2CH3或卤代甲基； A为N或CH； R3为甲基，如果A为CH，则另外还有氢； 用于制备这些化合物的过程和中间体，包含它们的组合物及其用于控制植物病原真菌的用途。5,6-二烷基-7-氨基咪唑嘧啶，其制备及其用于控制有害真菌的用途，以及包含这些化合物的组合物。
• 5,6-Dialkyl-7-Amino-Azolopyrimidines, Method For Their Production, Their Use For Controlling Pathogenic Fungi and Agents Containing Said Compounds
  申请人：Schafer Peter

  公开号：US20080125445A1

  公开（公告）日：2008-05-29

  5,6-Dialkyl-7-aminoazolopyrimidines of the formula I in which the substituents are as defined below: R 1 is alkyl or alkoxyalkyl, R 2 is alkyl, where R 1 and/or R 2 may be substituted according to the description, A is N or CH, and R 3 is CH 3 and, if A is CH, additionally hydrogen; processes and intermediates for preparing these compounds, compositions comprising them and their use for controlling phytopathogenic harmful fungi.

  公式I中的5,6-二烷基-7-氨基咪唑嘧啶，其中取代基如下所定义：R1为烷基或烷氧基烷基，R2为烷基，其中R1和/或R2可以根据描述进行取代，A为N或CH，R3为CH3，如果A为CH，则还包括氢原子；制备这些化合物的方法和中间体，包含它们的组合物以及它们用于控制植物病原真菌的用途。