4-Androsten-3-on | 2872-90-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 4-Androsten-3-on
• 英文别名: Androst-4-en-3-on；Testosteron；3-oxo-10.13-dimethyl-Δ⁴-tetradecahydro-1H-cyclopenta[a]phenanthrene；3-Oxo-10.13-dimethyl-Δ⁴-tetradecahydro-1H-cyclopenta[a]phenanthren；3-Oxo-delta4-steroid；10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
• CAS: 2872-90-4；23124-52-9
• 化学式: C₁₉H₂₈O
• 分子量: 272.431
• InChiKey: MSEZLHAVPJYYIQ-UHFFFAOYSA-N

物化性质

• 熔点：
  116-120 °C
• 沸点：
  390.6±9.0 °C(Predicted)
• 密度：
  1.05

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  3a,6-dimethyl-dodecahydro-cyclopenta[a]naphthalen-7-one 在 乙醚 、 sodium amide 作用下， 生成 4-Androsten-3-on
  参考文献：
  名称：

  Mukharji, Journal of the Indian Chemical Society, 1947, vol. 24, p. 91,96

  摘要：

  DOI：

文献信息

• BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
  申请人：Gouliaev Alex Haahr

  公开号：US20130281324A1

  公开（公告）日：2013-10-24

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.
• SYSTEMS AND METHODS FOR ANALYZING AN EXTRACTED SAMPLE USING AN IMMISCIBLE EXTRACTION SOLVENT
  申请人：PURDUE RESEARCH FOUNDATION

  公开号：US20160351381A1

  公开（公告）日：2016-12-01

  The invention generally relates to systems and methods for analyzing an extracted sample using an immiscible extraction solvent. In certain embodiments, the invention provides a system for analyzing an analyte in a sample. The system includes an ionization probe and a mass spectrometer. The ionization probe includes a hollow body that optionally includes a distal tip. The hollow body is configured such that there is no substrate within the body and no electrode disposed on a surface of the body. An electrode is at least partially disposed within the hollow body.
• [EN] GLYCO-PHOSPHORYLATED BIOLOGICALLY ACTIVE AGENTS<br/>[FR] AGENTS BIOLOGIQUEMENT ACTIFS GLYCO-PHOSPHORYLES
  申请人：BRAIN N BEYOND BIOTECH PVT LTD

  公开号：WO2007052308A2

  公开（公告）日：2007-05-10

  [EN] Abstract The present invention relates to a compound of formula I: (I) wherein DX is a radical of a biologically active agent comprising atom X; X is selected from O and N; and A is a radical of a saccharide, or an acid, salt, or ester thereof. Further, the invention relates to a pharmaceutical composition comprising compound of formula I, a process of preparing the same and method of management of tumor, inflammation, infection and promoting passage across blood-brain barrier.
  [FR] La présente invention concerne un composé de formule (I) dans laquelle DX représente un radical d'un agent biologiquement actif comprenant un atome X qui est choisi parmi O et N et A représente un radical d'un saccharide ou un acide, un sel ou un ester de celui-ci. Cette invention concerne également une composition pharmaceutique comprenant le composé de formule (I), un procédé pour la préparer, ainsi qu'un procédé pour maîtriser une tumeur, une inflammation ou une infection et pour promouvoir un passage à travers la barrière hémato-encéphalique.