D-Mannuronicacidlactone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氧环庚烷
• 英文名称: D-Mannuronicacidlactone
• 英文别名: 3,4,8-trihydroxy-2,6-dioxabicyclo[3.2.1]octan-7-one
• 化学式: C₆H₈O₆
• 分子量: 176.12
• InChiKey: NNKCVJYUFBVOMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  96.2
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• 5-ALA derivatives and use thereof
  申请人：UNIVERSITE DE GENEVE

  公开号：US10258690B2

  公开（公告）日：2019-04-16

  The present invention is directed to new 5-ALA derivatives, particles and formulation thereof, related methods of preparation and methods of use thereof. In particular, the invention relates to compounds of the invention, particles and formulation thereof useful in the treatment of a cancer and/or the diagnosis of a cancer cell such as in photodynamic therapy or photodynamic diagnosis.

  本发明涉及新的 5-ALA 衍生物、颗粒及其制剂、相关制备方法及其使用方法。特别是，本发明涉及本发明的化合物、颗粒及其制剂，可用于治疗癌症和/或诊断癌细胞，如光动力疗法或光动力诊断。
• 5-ALA DERIVATIVES AND USE THEREOF
  申请人：UNIVERSITE DE GENEVE

  公开号：US20180133320A1

  公开（公告）日：2018-05-17

  The present invention is directed to new 5-ALA derivatives, particles and formulation thereof, related methods of preparation and methods of use thereof. In particular, the invention relates to compounds of the invention, particles and formulation thereof useful in the treatment of a cancer and/or the diagnosis of a cancer cell such as in photodynamic therapy or photodynamic diagnosis.