4-Acetylamino-chinuclidin | 18955-78-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 奎宁环
• 英文名称: 4-Acetylamino-chinuclidin
• 英文别名: Acetamide, N-1-azabicyclo[2.2.2]oct-4-yl-；N-(1-azabicyclo[2.2.2]octan-4-yl)acetamide
• CAS: 18955-78-7
• 化学式: C₉H₁₆N₂O
• 分子量: 168.239
• InChiKey: QBBCDCAKMDTCPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• DIPHENYL SUBSTITUTED ALKANES
  申请人：Ogawa Anthony

  公开号：US20100190761A1

  公开（公告）日：2010-07-29

  The instant invention provides compounds of Formula I which are 5-lipoxygenase activating protein inhibitors: formula (I). Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

  本发明提供了式I的化合物，该化合物是5-脂氧合酶激活蛋白抑制剂：式(I)。式I的化合物可用作抗动脉粥样硬化、抗哮喘、抗过敏、抗炎和细胞保护剂。
• NOVEL CEPHEM COMPOUND HAVING CATECHOL OR PSEUDO-CATECHOL STRUCTURE
  申请人：Nishitani Yasuhiro

  公开号：US20140088302A1

  公开（公告）日：2014-03-27

  The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.
• US9334289B2
  申请人：——

  公开号：US9334289B2

  公开（公告）日：2016-05-10