6-vinyl-7-methoxy-2,2-dimethylchromene | 62458-61-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 6-vinyl-7-methoxy-2,2-dimethylchromene
• 英文别名: 6-ethenyl-7-methoxy-2,2-dimethylchromene
• CAS: 62458-61-1
• 化学式: C₁₄H₁₆O₂
• 分子量: 216.28
• InChiKey: RRUFTPKJXNXMAE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  英西卡林 在 正丁基锂 、 三氟化硼乙醚 、 二异丙胺 作用下， 以 四氢呋喃 、 苯 为溶剂， 反应 3.0h， 生成 6-vinyl-7-methoxy-2,2-dimethylchromene
  参考文献：
  名称：

  Bohlmann, Ferdinand; Stoehr, Frank-Michael, Liebigs Annalen der Chemie, 1980, # 2, p. 185 - 191

  摘要：

  DOI：

文献信息

• Methods for treating benign prostatic hypertrophy (BPH) symptoms using extract from Ageratum spp
  申请人：GE Nutrients, Inc.

  公开号：US11071763B2

  公开（公告）日：2021-07-27

  An herbal extract and constituents thereof for treatment of BPH and related aging symptoms in males and for addressing male health using extracts from Ageratum spp., including, but not limited to, Ageratum conyzoides, Ageratum coeruleum and Ageratum houstonianum, is disclosed herein. At least one compound of plants, and parts of plants, of Ageratum spp., such as, but not limited to, N,N-bis(trimethylsilyl)-2-phenyl-7-(trifluoromethyl)quinolon-4-amine, 3′,4′,5′,6′,7′,8-hexamethoxyflavone, Phytol, Precocene, caryophyllene, squalene, alpha-linolenic acid, (Z,Z)-9,12-octadecadienoic acid, Hexadecanoic acid, Hydrocoumarin, Encecaline-1-(7-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone, Senensetin-3,4,5,6,7-pentamethoxy flavone, Beta selinene, Stigmasterol, Beta sitosterol, Quercetin, Quercetin-3-O-rhamnosylglucoside, Linoleic acid, or Conyzorigin can be extracted utilizing a Common Plant Extraction Approach (CPEA). The extraction of compounds can be performed utilizing an ethanol solvent and sterile water solvent and/or ethanol mixed with sterile water (i.e., hydro-alcoholic solvents) separately and the concentrated materials obtained as these solvents systems are pooled together (or maintained separately) in order to obtain an herbal extract for the treatment of BPH.

  本文公开了一种草本提取物及其成分，用于治疗男性良性前列腺增生症和相关衰老症状，并利用龙胆草属植物（包括但不限于Ageratum conyzoides、Ageratum coeruleum和Ageratum houstonianum）的提取物解决男性健康问题。本文公开了至少一种龙舌兰属植物和植物部分的化合物，如，但不限于，Ageratum conyzoides、Ageratum coeruleum 和 Ageratum houstonianum、例如，但不限于，N,N-双（三甲基硅基）-2-苯基-7-（三氟甲基）喹啉-4-胺、3′,4′,5′,6′,7′,8-六甲氧基黄酮、植物醇、前胡烯、叶黄素、角鲨烯、α-亚麻酸、(Z,Z)-9,12-十八碳二烯酸、十六烷酸、氢化香豆素、可利用普通植物提取方法 (CPEA) 提取 Encecaline-1-(7-methoxy-2,2-dimethyl-2H-chromen-6-yl)ethanone, Senensetin-3,4,5,6,7-pentamethoxy flavone, Beta selinene, Stigmasterol, Beta sitosterol, Quercetin, Quercetin-3-O-rhamnosylglucoside, Linoleic acid 或 Conyzorigin。化合物的提取可分别使用乙醇溶剂和无菌水溶剂和/或乙醇与无菌水混合溶剂（即水醇溶剂），然后将这些溶剂系统得到的浓缩物集中在一起（或分别保存），以获得用于治疗良性前列腺增生症的草药提取物。
• Herbal preparation for stimulation of hair growth, control of hair fall, dandruff and infections thereof using Ageratum spp
  申请人：GE Nutrients, Inc.

  公开号：US11357809B2

  公开（公告）日：2022-06-14

  This disclosure describes herbal preparations for the stimulation of hair growth, control of hair fall, control of dandruff, and control of dandruff-related infections thereof, using herbaceous plants, Ageratum spp. Processes for preparing the herbal preparations and methods for using them are also disclosed. Such an herbal preparation using plants, Ageratum spp. can be utilized as an efficient hair care solution in a wide range of hair growth related problems of humans in a cost-effective manner.

  本公开描述了使用草本植物龙葵属（Ageratum spp）刺激头发生长、控制头发脱落、控制头皮屑和控制头皮屑相关感染的草本制剂，还公开了制备该草本制剂的工艺及其使用方法。这种使用龙胆草属植物的草药制剂可作为一种高效的头发护理解决方案，以经济有效的方式解决人类各种与头发生长相关的问题。
• HERBAL PREPARATION FOR STIMULATION OF HAIR GROWTH, CONTROL OF HAIR FALL, DANDRUFF AND INFECTIONS THEREOF USING AGERATUM SPP.
  申请人：Gencor Armats Biotek Pvt. Ltd

  公开号：EP2885054A1

  公开（公告）日：2015-06-24
• HERBAL EXTRACT COMPOSITION AND METHOD FOR IMPROVING AND MANAGING BENIGN PROSTATIC HYPERTROPHY (BPH) AND RELATED AGING SYMPTOMS USING EXTRACT FROM AGERATUM SPP
  申请人：GE Nutrients, Inc.

  公开号：EP3813943A1

  公开（公告）日：2021-05-05
• HERBAL PREPARATION FOR STIMULATION OF HAIR GROWTH, CONTROL OF HAIR FALL, DANDRUFF AND INFECTIONS THEREOF USING AGERATUM SPP
  申请人：GE Nutrients, Inc.

  公开号：EP4013438A1

  公开（公告）日：2022-06-22