5-Bromo-2-[(3-bromo-2,2-dimethyl-6-methylidenecyclohexyl)methyl]-4-methoxyphenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-Bromo-2-[(3-bromo-2,2-dimethyl-6-methylidenecyclohexyl)methyl]-4-methoxyphenol
• 化学式: C₁₇H₂₂Br₂O₂
• 分子量: 418.2
• InChiKey: UHRXKJFPPKYYEC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT<br/>[FR] EXTRAITS D'ALGUES, COMPOSÉS ISOLÉS ET PROCÉDÉS DE TRAITEMENT
  申请人：UNIV FLORIDA

  公开号：WO2019113383A1

  公开（公告）日：2019-06-13

  The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated diseases and diseases mediated through the activation of the Nrf2-ARE (antioxidant response element) pathway, including proliferative diseases and disorders, Alzheimer's disease, stroke, and certain diseases and disorders of aging and associated with aging and exposure, by use of the extracts, compounds, and compositions thereof.

  本发明涉及海藻提取物组合物、隔离工艺、隔离的活性成分以及治疗受试者疾病、疾病和病情的方法，包括通过使用提取物、化合物和其组合物治疗反应性氧化物种（ROS）介导的疾病和通过激活Nrf2-ARE（抗氧化剂反应元素）途径介导的疾病，包括增殖性疾病和疾病、老年痴呆症、中风以及与老化和暴露相关的某些疾病和疾病。
• SEAWEED EXTRACTS, ISOLATED COMPOUNDS, AND METHODS OF TREATMENT
  申请人：University of Florida Research Foundation, Incorporated

  公开号：US20210161980A1

  公开（公告）日：2021-06-03

  The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated diseases and diseases mediated through the activation of the Nrf2-ARE (antioxidant response element) pathway, including proliferative diseases and disorders, Alzheimer's disease, stroke, and certain diseases and disorders of aging and associated with aging and exposure, by use of the extracts, compounds, and compositions thereof.