2-(4-Hydroxyphenyl)ethyl 4-formyl-3-(2-oxoethyl)hex-4-enoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-(4-Hydroxyphenyl)ethyl 4-formyl-3-(2-oxoethyl)hex-4-enoate
• 英文别名: 2-(4-hydroxyphenyl)ethyl 4-formyl-3-(2-oxoethyl)hex-4-enoate
• 化学式: C₁₇H₂₀O₅
• 分子量: 304.34
• InChiKey: VPOVFCBNUOUZGG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  22
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  80.7
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Method and system to reduce porosity in composite structures
  申请人：The Boeing Company

  公开号：EP2703429A1

  公开（公告）日：2014-03-05

  In an embodiment of the disclosure, there is provided a method to reduce porosity in a composite structure. The method adds an additive to a resin material to form an additive-resin mixture. The method combines the additive-resin mixture with reinforcement fibers to form a composite prepreg material, and in turn, a composite structure. The method heat cures the composite structure in a heating apparatus under a vacuum device at the resin cure temperature, heats the composite structure to an increased temperature above the additive phase transition temperature, and maintains the increased temperature for a time period sufficient. The method reduces the increased temperature back down to the resin cure temperature to allow the additive gas to undergo a phase transition to a condense phase, resulting in a substantially reduced vacuum pressure, resulting in a reduction in a porosity of the composite structure.

  在本公开的一个实施方案中，提供了一种减少复合材料结构中孔隙率的方法。该方法将添加剂添加到树脂材料中，形成添加剂-树脂混合物。该方法将添加剂-树脂混合物与增强纤维相结合，形成复合预浸料，进而形成复合结构。该方法在真空设备下的加热装置中，在树脂固化温度下对复合结构进行热固化，将复合结构加热到高于添加剂相变温度的升高温度，并在足够长的时间内保持该升高温度。该方法将升高的温度降至树脂固化温度，使添加剂气体发生相变，进入凝结相，从而使真空压力大大降低，导致复合材料结构的孔隙率降低。
• AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS
  申请人：N-Zyme BioTec GmbH

  公开号：EP3409766A1

  公开（公告）日：2018-12-05

  The present invention relates to a polypeptide having esterase activity selected from the group consisting of (a) a polypeptide comprising the amino acid sequence of SEQ ID NO: 7; (b) a polypeptide that is at least 60 % identical to the amino acid sequence of SEQ ID NO: 7 and which is characterized by having an esterase activity; (c) a polypeptide encoded by a nucleic acid molecule which is at least 60 % identical to the nucleic acid sequence of SEQ ID NO: 5 or 6 wherein said polypeptide is characterized by having an esterase activity; (d) a polypeptide encoded by the nucleic acid molecule of SEQ ID NO: 5 or 6; and (e) a polypeptide encoded by the complementary sequence of a nucleic acid molecule that is able to hybridize with the nucleic acid molecule of SEQ ID NO: 5 or 6. Further, the present invention relates to a polypeptide having esterase activity selected from the group consisting of SEQ ID NO: 24 and 37 (as encoded by nuleic acid molecule of SEQ ID NO: 22 or 23 and SEQ ID NO: 35 and 36). The present invention also relates to a method for the production of oleacein, oleocanthal, or decarboxymethyl elenolic acid dialdehyde (DEDA) comprising the use of the esterase of the present invention. to an organism, preferably a plant cell, genetically engineered with a nucleic acid molecule encoding a polypeptide characterized by having an esterase activity or the vector of the present invention. The present invention also relates to a method for the production of oleacein, oleocanthal, and/or decarboxymethyl elenolic acid dialdehyde (DEDA) comprising the use of the esterase of the present invention.

  本发明涉及一种具有酯酶活性的多肽，该多肽选自由以下组成的组 (a) 包含 SEQ ID NO: 7 的氨基酸序列的多肽；(b) 与 SEQ ID NO: 7 的氨基酸序列至少 60% 相同的多肽，其特征在于具有酯酶活性；(c) 由核酸分子编码的多肽，该核酸分子与 SEQ ID NO: 5 或 6 的核酸序列至少 60% 相同，其中所述多肽的特征在于具有酯酶活性；(d) 由 SEQ ID NO: 5 或 6 的核酸分子编码的多肽；以及(e) 由 SEQ ID NO: 6 的核酸分子编码的多肽：5或6的核酸分子编码的多肽，其中所述多肽的特征在于具有酯酶活性；(d)由SEQ ID NO：5或6的核酸分子编码的多肽；以及(e)由能够与SEQ ID NO：5或6的核酸分子杂交的核酸分子的互补序列编码的多肽。此外，本发明涉及一种具有酯酶活性的多肽，该多肽选自 SEQ ID NO: 24 和 37（由 SEQ ID NO: 22 或 23 和 SEQ ID NO: 35 和 36 的核酸分子编码）组成的组。本发明还涉及一种生产油菜素、油菜醛或脱羧甲基烯醇酸二醛（DEDA）的方法，包括使用本发明的酯酶。本发明涉及一种生物体，最好是植物细胞，其基因工程中含有编码具有酯酶活性的多肽的核酸分子或本发明的载体。本发明还涉及一种生产油菜素、油菜醛和/或脱羧甲基烯醇酸二醛（DEDA）的方法，包括使用本发明的酯酶。
• METHODS OF PRODUCING AND USING NUTRITIONAL AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE ONE OR MORE ACTIVE SUBSTANCES
  申请人：Denk Erwin

  公开号：US20100173856A1

  公开（公告）日：2010-07-08

  Methods for producing a composition that includes an active agent, nutraceutical and pharmaceuticals compositions, and methods for ameliorating and/or treating a disease using the composition that includes an active substance are described herein. More particularly, methods for producing a composition that contains one or more active substances such as oleocanthal, pharmaceutical compositions that include one or more active substances such as oleocanthal, and methods of ameliorating and/or treating inflammation using compositions that contains one or more active substances such as oleocanthal are described.
• Method and System to Reduce Porosity in Composite Structures
  申请人：Humfeld Keith Daniel

  公开号：US20140060731A1

  公开（公告）日：2014-03-06

  In an embodiment of the disclosure, there is provided a method to reduce porosity in a composite structure. The method adds an additive to a resin material to form an additive-resin mixture. The method combines the additive-resin mixture with reinforcement fibers to form a composite prepreg material, and in turn, a composite structure. The method heat cures the composite structure in a heating apparatus under a vacuum device at the resin cure temperature, heats the composite structure to an increased temperature above the additive phase transition temperature, and maintains the increased temperature for a time period sufficient. The method reduces the increased temperature back down to the resin cure temperature to allow the additive gas to undergo a phase transition to a condense phase, resulting in a substantially reduced vacuum pressure, resulting in a reduction in a porosity of the composite structure.
• US8647548B1
  申请人：——

  公开号：US8647548B1

  公开（公告）日：2014-02-11