5-[2-(Methylamino)ethyl]benzene-1,2,3-triol

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-[2-(Methylamino)ethyl]benzene-1,2,3-triol
• 英文别名: 5-[2-(methylamino)ethyl]benzene-1,2,3-triol
• 化学式: C₉H₁₃NO₃
• 分子量: 183.2
• InChiKey: XBQVPOIMYUOPSA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  72.7
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• HYDROGEL USING, AS SUBSTRATE, HYALURONIC ACID DERIVATIVE MODIFIED WITH GALLOL GROUP AND USE THEREOF
  申请人：AMTIXBIO CO., LTD

  公开号：US20200230288A1

  公开（公告）日：2020-07-23

  The present invention provides a hydrogel platform using, as a substrate, hyaluronic acid (HA) conjugated to a pyrogallol (PG) moiety. The HA-PG conjugate of the present invention can be rapidly crosslinked by two different methods, in each of which an oxidizing agent is used or a pH is adjusted. The hydrogel of the present invention can not only have excellent biocompatibility, but also can have efficiently controlled physical characteristics such as a crosslinking rate, elasticity, and adhesive strength, depending on each crosslinking method. On the basis of such excellent stability and functionality, the hydrogel of the present invention can be used in various fields including drug delivery, biopharmaceutical materials such as a wound healing agent or anti-adhesive agent, medicines, and cosmetic products.