isomyrtucommulone B

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: isomyrtucommulone B
• 英文别名: 6,8-dihydroxy-2,2,4,4-tetramethyl-7-(2-methylpropanoyl)-9-propan-2-yl-9H-xanthene-1,3-dione
• 化学式: C₂₄H₃₀O₆
• 分子量: 414.499
• InChiKey: YANZMYIELXMLTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  30
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  myrtucommulone A 以 氘代二甲亚砜 为溶剂， 反应 48.0h， 生成 isomyrtucommulone B
  参考文献：
  名称：

  Oligomeric Acylphloroglucinols from Myrtle (Myrtus communis)

  摘要：

  The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.

  DOI：

  10.1021/np010441b

文献信息

• Oligomeric Acylphloroglucinols from Myrtle (<i>Myrtus communis</i>)
  作者：Giovanni Appendino、Federica Bianchi、Alberto Minassi、Olov Sterner、Mauro Ballero、Simon Gibbons

  DOI：10.1021/np010441b

  日期：2002.3.1

  The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of. myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.