N-(3-methylbutyl)-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫杂环戊烷
• 英文名称: N-(3-methylbutyl)-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
• 化学式: C₁₅H₂₇N₃O₂S
• 分子量: 313.5
• InChiKey: YVTTZQWFWLOADF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  95.5
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• METHODS OF SYNTHESIZING LABELED NUCLEOSIDES
  申请人：Singular Genomics Systems, Inc.

  公开号：US20190077726A1

  公开（公告）日：2019-03-14

  Disclosed herein, inter alia, are compounds, compositions, and methods of synthesizing labeled nucleosides.

  在此披露的内容包括化合物、组合物和合成标记核苷的方法。
• Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
  申请人：Ju Jingyue

  公开号：US11085076B2

  公开（公告）日：2021-08-10

  Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

  本文特别披露了用于核酸测序的化合物、组合物及其使用方法。
• MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR
  申请人：XIAMEN SINOPEG BIOTECH CO., LTD.

  公开号：US20170312363A1

  公开（公告）日：2017-11-02

  Disclosed are a multifunctionalized polyethylene glycol derivative and a preparation method therefor. The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n 1 , n 2 , n 3 , and n 4 respectively are the degrees of polymerization of the branch chains, U 1 and U 2 are trivalent branching groups connecting the core LPEG to two of the PEG branch chains, F 1 and F 2 contain a functional group or a protected form R 01 thereof and may or may not contain a branched group G, correspondingly, the number of R 01 is one or more, F 1 and F 2 are either identical or different, any one linking group in the molecule or any linking group formed with an adjacent heteroatom group can either remain stable or be degraded, and any one PEG segment in the molecule is discretely polydispersed or monodispersed. The multifunctional polyethylene glycol is flexible and diverse in terms of branch structures and the lengths of branching arms, has various parameters and performance indicators that are adjustable and easy to control, and has a broad applicability.
• NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF
  申请人：THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

  公开号：US20200069717A1

  公开（公告）日：2020-03-05

  Disclosed herein, inter alia, are compounds, compositions, and methods of thereof in the sequencing a nucleic acid.
• DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS
  申请人：Ju Jingyue

  公开号：US20220411860A1

  公开（公告）日：2022-12-29

  Disclosed herein, inter alfa, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.